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Merck
CN

243973

Sodium bisulfite

ACS reagent

Synonym(s):

Sodium hydrogensulfite

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About This Item

Empirical Formula (Hill Notation):
NaHSO3
CAS Number:
Molecular Weight:
104.06
MDL number:
UNSPSC Code:
12352302
PubChem Substance ID:
NACRES:
NA.21
Grade:
ACS reagent
Form:
powder or crystals
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grade

ACS reagent

Quality Segment

form

powder or crystals

concentration

≥58.5% SO2

impurities

≤0.005% insolubles

pH

4.3 (10 g/L)

anion traces

chloride (Cl-): ≤0.02%

cation traces

Fe: ≤0.002%, heavy metals (as Pb): ≤0.001%

SMILES string

[Na+].OS([O-])=O

InChI

1S/Na.H2O3S/c;1-4(2)3/h;(H2,1,2,3)/q+1;/p-2

InChI key

DWAQJAXMDSEUJJ-UHFFFAOYSA-L

General description

The aqueous solutions of sodium bisulfite are acidic in nature. Degradation of sodium bisulfite with acid forms sulfur dioxide gas.
Sodium bisulfite is a widely used industrial chemical as a reducing agent, catalyst, and preservative in pharmaceuticals and foods due to its antioxidative and antibacterial effects.

Application

Sodium bisulfite (NaHSO3) has been used as a reagent to compose the immunoprecipitation (IP) buffer to chemically modify DNA and to synthesize arsenolipids (AsL).
It can also be used as a reagent during the synthesis of 5,6-dihydrouracil-6-sulfonate.
Sodium bisulfite can be used as:
  • A reagent to synthesize aldehyde-bisulfite adducts from aromatic and aliphatic aldehydes.
  • A catalyst in the solvent-free etherification of aromatic/aliphatic alcohols to synthesize symmetric and unsymmetric ethers via intermolecular dehydration.
  • An additive in the copper-catalyzed homocoupling of ketoxime carboxylates to synthesize symmetrical pyrroles.

Disclaimer

The product is not intendedfor use as a biocide under global biocide regulations, including but notlimited to the US EPA′s Federal Insecticide Fungicide and Rodenticide Act, theEuropean Biocidal Products Regulation, Canada’s Pest Management RegulatoryAgency, Turkey’s Biocidal Products Regulation, Korea’s Consumer ChemicalProducts and Biocide Safety Management Act (K-BPR), and others.


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Warning

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Hazard Classifications

Acute Tox. 4 Oral

supp_hazards

Storage Class

13 - Non Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable



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