320269
Dichloromethane
ACS reagent, ≥99.5%, contains 40-150 ppm amylene as stabilizer
Synonym(s):
methylene chloride, Methylene chloride
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About This Item
Empirical Formula (Hill Notation):
CH2Cl2
CAS Number:
Molecular Weight:
84.93
Beilstein:
1730800
EC Number:
MDL number:
UNSPSC Code:
12352101
PubChem Substance ID:
NACRES:
NA.04
Grade:
ACS reagent
Assay:
≥99.5%
Bp:
39.8-40 °C (lit.)
Vapor pressure:
24.45 psi ( 55 °C)
6.83 psi ( 20 °C)
6.83 psi ( 20 °C)
grade
ACS reagent
Quality Level
Agency
suitable for EPA 1613
vapor density
2.9 (vs air)
vapor pressure
24.45 psi ( 55 °C)
6.83 psi ( 20 °C)
Assay
≥99.5%
form
liquid
autoignition temp.
1223 °F
contains
40-150 ppm amylene as stabilizer
expl. lim.
22 %
dilution
(for analytical testing)
impurities
Free halogens, passes test
≤0.0003 meq/g Titr. acid
≤0.02% water
evapn. residue
≤0.002%
color
APHA: ≤10
clear
refractive index
n20/D 1.424 (lit.)
bp
39.8-40 °C (lit.)
mp
−95 °C (lit.)
density
1.325 g/mL at 25 °C (lit.)
SMILES string
ClCCl
InChI
1S/CH2Cl2/c2-1-3/h1H2
InChI key
YMWUJEATGCHHMB-UHFFFAOYSA-N
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General description
Our premium ACS solvents are ideal for routine chemical synthesis, drying, purification, and critical labware cleaning. They meet or exceed the rigorous standards of the American Chemical Society (ACS), ensuring high-quality results for your research needs.
Premium ACS Solvents: Our solvents meet or exceed the stringent standards set by the American Chemical Society, ensuring high quality and reliability for your laboratory applications.
Replicable and Publishable Results: Designed for consistency, our solvents deliver results that can be reliably reproduced, making them ideal for research that requires publication.
Versatile Applications: Suitable for routine chemical synthesis, drying, purification, and critical labware cleaning, our solvents cater to a wide range of research needs in the laboratory.
Premium ACS Solvents: Our solvents meet or exceed the stringent standards set by the American Chemical Society, ensuring high quality and reliability for your laboratory applications.
Replicable and Publishable Results: Designed for consistency, our solvents deliver results that can be reliably reproduced, making them ideal for research that requires publication.
Versatile Applications: Suitable for routine chemical synthesis, drying, purification, and critical labware cleaning, our solvents cater to a wide range of research needs in the laboratory.
Application
- Rapid and Comprehensive Analysis of 41 Harmful Substances in Multi-Matrix Products by Gas Chromatography-Mass Spectrometry Using Matrix-Matching Calibration Strategy.: This research uses gas chromatography-mass spectrometry (GC-MS) to analyze harmful substances across various matrices. Dichloromethane is employed as a solvent in the preparation phase, highlighting its application in ensuring accurate and efficient analytical results (Wang Y et al., 2024).
- Brunonianines D-F, three new C19-diterpenoid alkaloids from the Delphinium brunonianum, with therapeutic effect on ovarian cancer in vitro and in vivo.: This study identifies new alkaloids with potential anti-cancer properties, where dichloromethane is utilized in the extraction and isolation processes. Its effectiveness in separating and preserving delicate compounds is critical for their pharmacological evaluation (Li Q et al., 2024).
- LC-HRMS and GC-MS Profiling of Urine Free Cortisol, Cortisone, 6Β-, and 18-Hydroxycortisol for the Evaluation of Glucocorticoid and Mineralocorticoid Disorders.: Utilizes LC-HRMS and GC-MS to profile hormones in urine, with dichloromethane being crucial in the extraction process. This method ensures precision and sensitivity in hormone measurement, essential for diagnosing endocrine disorders (Casals G et al., 2024).
- Determination of vancomycin and meropenem in serum and synovial fluid of patients with prosthetic joint infections using UPLC-MS/MS.: Features a method to measure antibiotics in biological fluids, where dichloromethane is used to prepare samples. This study underscores the solvent′s role in achieving high resolution and detection limits in clinical diagnostics (He J et al., 2024).
Features and Benefits
ACS solvents meet or exceed the high standards of the American Chemical Society (ACS) ,with test specifications that are specialized to every compound. According to the American Chemical Society, ACS reagent grade implies that it is a substance of sufficient purity to be used in most chemical analyses or reactions.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Central nervous system
Storage Class Code
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK
WGK 2
Flash Point(F)
does not flash
Flash Point(C)
does not flash
Regulatory Information
危险化学品
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Helen Harrington et al.
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Dipyridine-chromium (VI) oxide oxidation of alcohols in dichloromethane.
Collins JC, et al.
Tetrahedron Letters, 9(30), 3363-3366 (1968)
Effect of activated carbon content in TiO2-loaded activated carbon on photodegradation behaviors of dichloromethane.
Torimoto T, et al.
Journal of Photochemistry and Photobiology A: Chemistry, 103(1), 153-157 (1997)
Myat Noe Hsu et al.
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