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Sigma-Aldrich

Glycerol

puriss. p.a., ACS reagent, anhydrous, dist., ≥99.5% (GC)

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Synonym(s):
1,2,3-Propanetriol, Glycerin
Linear Formula:
HOCH2CH(OH)CH2OH
CAS Number:
56-81-5
Molecular Weight:
92.09
Beilstein:
635685
EC Number:
200-289-5
MDL number:
MFCD00004722
PubChem Substance ID:
329757522
NACRES:
NA.21

grade

ACS reagent
puriss. p.a.

Quality Level

200

vapor density

3.1 (vs air)

vapor pressure

<1 mmHg ( 20 °C)

Assay

≥99.5% (GC)

form

viscous liquid

autoignition temp.

698 °F

quality

dist.

expl. lim.

2.6-11.3 %

technique(s)

electrophoresis: suitable

impurities

acrolein and glucose, in accordance
 substances darkened by H2SO4, in accordance
≤0.05% fatty acid esters (as butyric acid)
≤0.1% water

ign. residue

≤0.005%

refractive index

n20/D 1.474 (lit.)

pH

5.5-8

bp

182 °C/20 mmHg (lit.)

mp

20 °C (lit.)

density

1.25 g/mL (lit.)

anion traces

chloride (Cl-): ≤1 mg/kg
sulfate (SO42-): ≤10 mg/kg

cation traces

Ca: ≤5 mg/kg
Cd: ≤1 mg/kg
Co: ≤1 mg/kg
Cr: ≤1 mg/kg
Cu: ≤1 mg/kg
Fe: ≤1 mg/kg
K: ≤20 mg/kg
Mg: ≤1 mg/kg
Mn: ≤1 mg/kg
NH4+: ≤5 mg/kg
Na: ≤20 mg/kg
Ni: ≤1 mg/kg
Pb: ≤1 mg/kg
Zn: ≤1 mg/kg

SMILES string

OCC(O)CO

InChI

1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2

InChI key

PEDCQBHIVMGVHV-UHFFFAOYSA-N

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General description

Glycerol is widely used in industries based on food, polymer, resins, tobacco, detergents, explosives, drugs and personal care products. It is most commonly employed cheap feedstock in the chemical industry. Its transformation to various commercial value-added chemicals has been proposed. A fast enzymatic assay for the determination of glycerol based on its reaction with ATP has been described.

Application

Glycerol has been used in the synthesis of poly(glycerol sebacate) (PGS) pre-polymer, which is required for the fabrication of PGS scaffolds. It may be employed to protect the human red blood-cells from damage during the process of freezing and thawing.
Glycerol is used both in sample preparation and gel formation for polyacrylamide gel electrophoresis. Glycerol (5-10%) increases the density of a sample so that the sample will layer at the bottom of a gel′s sample well. Glycerol is also used to aid in casting gradient gels and as a protein stabilizer and storage buffer component.

greener alternative product

Product No.
Description
Pricing

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

390.2 °F - Pensky-Martens closed cup

Flash Point(C)

199 °C - Pensky-Martens closed cup

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A rapid enzymatic assay for glycerol.
Garland PB and Randle PJ.
Nature, 196, 987 - 988 (1962)
Nafiseh Masoumi et al.
Journal of biomedical materials research. Part A, 101(1), 104-114 (2012-07-25)
Microfabricated poly(glycerol sebacate) (PGS) scaffolds may be applicable to tissue engineering heart valve leaflets by virtue of their controllable microstructure, stiffness, and elasticity. In this study, PGS scaffolds were computationally designed and microfabricated by laser ablation to match the anisotropy
The mechanism of the protective action of glycerol against haemolysis by freezing and thawing.
J E LOVELOCK
Biochimica et biophysica acta, 11(1), 28-36 (1953-05-01)
Mario Pagliaro et al.
Angewandte Chemie (International ed. in English), 46(24), 4434-4440 (2007-05-02)
Today, industrial plants that produce glycerol are closing down and others are opening that use glycerol as a raw material, owing to the large surplus of glycerol formed as a by-product during the production of biodiesel. Research efforts to find
Shelley L Forrest et al.
The Journal of comparative neurology, 522(17), 3900-3927 (2014-07-22)
Artemin is a member of the glial cell line-derived neurotrophic factor (GDNF) family that has been strongly implicated in development and regeneration of autonomic nerves and modulation of nociception. Whereas other members of this family (GDNF and neurturin) primarily target
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