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Merck
CN

537551

Sigma-Aldrich

Ethylene glycol butyl ether

≥99%

Synonym(s):

2-Butoxyethanol, Butyl glycol

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About This Item

Linear Formula:
CH3(CH2)3OCH2CH2OH
CAS Number:
111-76-2
Molecular Weight:
118.17
Beilstein:
1732511
EC Number:
203-905-0
MDL number:
MFCD00002884
UNSPSC Code:
12352104
PubChem Substance ID:
329757985
NACRES:
NA.21
Assay:
≥99%
Bp:
169-172.5 °C (lit.)
Vapor pressure:
<1 mmHg ( 20 °C)
10 mmHg ( 81 °C)

Key Documents

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vapor density

4.1 (vs air)

Quality Level

200

vapor pressure

<1 mmHg ( 20 °C)
10 mmHg ( 81 °C)

Assay

≥99%

form

liquid

autoignition temp.

473 °F

expl. lim.

10.6 %

impurities

≤0.10% (water)

refractive index

n20/D 1.419 (lit.)

bp

169-172.5 °C (lit.)

mp

−75 °C (lit.)

solubility

water: soluble

density

0.902 g/mL at 25 °C (lit.)

SMILES string

CCCCOCCO

InChI

1S/C6H14O2/c1-2-3-5-8-6-4-7/h7H,2-6H2,1H3

InChI key

POAOYUHQDCAZBD-UHFFFAOYSA-N

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General description

Ethylene glycol butyl ether (EGBE) is an ethylene oxide-based glycol ether solvent commonly used in the coatings industry. Its relative evaporation rate with respect to n-butyl acetate has been reported to be 0.07. Its toxicity has been assessed. The effect of EGBE as a thickening solvent during acrylic latex synthesis has been investigated.

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H302,H315,H319,H331

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Flash Point(F)

152.6 °F - Pensky-Martens closed cup

Flash Point(C)

67 °C - Pensky-Martens closed cup

Regulatory Information

危险化学品
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Certificates of Analysis (COA)

Lot/Batch Number
SHBS9285
SHBS3781
SHBR6506
SHBR2784
SHBQ4916

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Reproductive toxicology. Ethylene glycol monobutyl ether.
Environmental health perspectives, 105 Suppl 1, 217-218 (1997-02-01)
A novel alkali and cosolvent thickening mechanism for latex.
He L, et al.
New. J. Chem., 39(11), 8984-8992 (2015)
R L Smith
Environmental health perspectives, 57, 1-4 (1984-08-01)
Ethylene oxide-based glycol ether and glycol ether ester solvents have been used in the coatings industry for the past fifty years. Because of their excellent performance properties (evaporation rate, blush resistance, flow-out and leveling properties, solubility for coating resins, solvent
G Amir et al.
The British journal of oral & maxillofacial surgery, 49(1), 21-25 (2009-12-26)
Female rats develop haemolytic anaemia and disseminated thrombosis and infarction in multiple organs, including bone, when exposed to 2-butoxyethanol (BE). There is growing evidence that vascular occlusion of the subchondral bone may play a part in some cases of osteoarthritis.
Daphna Laifenfeld et al.
Toxicological sciences : an official journal of the Society of Toxicology, 113(1), 254-266 (2009-10-09)
To understand the molecular mechanisms underlying compound-induced hemangiosarcomas in mice, and therefore, their human relevance, a systems biology approach was undertaken using transcriptomics and Causal Network Modeling from mice treated with 2-butoxyethanol (2-BE). 2-BE is a hemolytic agent that induces
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