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Merck
CN

579548

Diethylene glycol methyl ether

ReagentPlus®, ≥99.0%

Synonym(s):

2-(2-Methoxyethoxy)ethanol, Methyldiglycol

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About This Item

Linear Formula:
CH3OCH2CH2OCH2CH2OH
CAS Number:
111-77-3
Molecular Weight:
120.15
UNSPSC Code:
12352104
NACRES:
NA.21
PubChem Substance ID:
329758379
EC Number:
203-906-6
Beilstein/REAXYS Number:
1697812
MDL number:
MFCD00002871
Assay:
≥99.0%
Bp:
194 °C (lit.)
Vapor pressure:
0.2 mmHg ( 20 °C)

Key Documents

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InChI

1S/C5H12O3/c1-7-4-5-8-3-2-6/h6H,2-5H2,1H3

SMILES string

COCCOCCO

InChI key

SBASXUCJHJRPEV-UHFFFAOYSA-N

vapor density

4.14 (vs air)

vapor pressure

0.2 mmHg ( 20 °C)

product line

ReagentPlus®

assay

≥99.0%

form

liquid

autoignition temp.

221 °C

expl. lim.

1.38-22.7 %

dilution

(for general lab use)

impurities

≤0.1% (water)

refractive index

n20/D 1.426 (lit.)

bp

194 °C (lit.)

mp

−70 °C (lit.)

density

1.023 g/mL at 25 °C (lit.)

Quality Level

100

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General description

Diethylene glycol methyl ether is an organic compound that is commonly used as an industrial solvent. It is used as a potential solvent for the separation of aromatic-paraffinic compounds.

Application


  • Composition-explicit distillation curves of diesel fuel with glycol ether and glycol ester oxygenates: fuel analysis metrology to enable decreased particulate emissions.: Investigates the incorporation of diethylene glycol methyl ether into diesel fuels to reduce particulate emissions. This research is vital for environmental science, focusing on improving air quality and reducing the ecological impact of diesel engines (Smith BL et al., 2008).

Legal Information

Product of Dow Chemical.
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H360D

Hazard Classifications

Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 1

flash_point_f

188.6 °F - closed cup

flash_point_c

87 °C - closed cup

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Certificates of Analysis (COA)

Lot/Batch Number
MKCZ2556
MKCW5533
MKCV9429
MKCV7699
MKCV1664

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B D Hardin et al.
Fundamental and applied toxicology : official journal of the Society of Toxicology, 6(3), 430-439 (1986-04-01)
Diethylene glycol monomethyl ether (diEGME) was one of 15 glycols tested in CD-1 mice using a short-term in vivo reproductive toxicity assay (Chernoff/Kavlock test). Because results were strongly suggestive of potential reproductive toxicity, a teratology study was conducted in Sprague-Dawley
Hao Zhu et al.
Chemical communications (Cambridge, England), 48(96), 11766-11768 (2012-11-02)
Rlyso, a highly selective and sensitive pH sensor, can stain lysosomes with a novel lysosome-locating group, methylcarbitol. Rlyso was successfully used to detect lysosomal pH changes during apoptosis or induced by chloroquine while avoiding the "alkalizing effect" on lysosomes of
R R Miller et al.
Fundamental and applied toxicology : official journal of the Society of Toxicology, 5(6 Pt 1), 1174-1179 (1985-12-01)
Male and female Fischer 344 rats were exposed to 0, 30, 100, or 216 ppm diethylene glycol monomethyl ether (DEGME) vapors (0, 0.15, 0.49, or 1.06 mg/liter) 6 hr/day, 5 days/week, for 13 weeks. The 216-ppm exposure level was the
Induction of r-GTP by ethylene glycol monomethyl ether.
T Kawamoto et al.
Toxicology and industrial health, 7(5-6), 473-478 (1991-09-01)
T Kawamoto et al.
Toxicology, 62(3), 265-274 (1990-06-01)
Glycol ethers have been extensively used in industry over the past 40-50 years. Numerous studies on the toxicity of glycol ethers have been performed, however, the effects of glycol ethers on the hepatic drug metabolizing enzymes are still unknown. We
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