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T59803

Sigma-Aldrich

Triethylene glycol dimethyl ether

ReagentPlus®, 99%

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Synonym(s):
1,2-Bis(2-methoxyethoxy)ethane, Dimethyltriglycol, NSC 66400, Triglyme
Linear Formula:
CH3O(CH2CH2O)3CH3
CAS Number:
112-49-2
Molecular Weight:
178.23
Beilstein:
1700630
EC Number:
203-977-3
MDL number:
MFCD00008504
PubChem Substance ID:
329826836
NACRES:
NA.21

vapor density

>4.7 (vs air)

Quality Level

100

product line

ReagentPlus®

Assay

99%

form

liquid

autoignition temp.

375 °F

expl. lim.

8 %

refractive index

n20/D 1.423 (lit.)

bp

216 °C (lit.)

mp

−45 °C (lit.)

density

0.986 g/mL at 25 °C (lit.)

SMILES string

COCCOCCOCCOC

InChI

1S/C8H18O4/c1-9-3-5-11-7-8-12-6-4-10-2/h3-8H2,1-2H3

InChI key

YFNKIDBQEZZDLK-UHFFFAOYSA-N

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General description

Triethyleneglycol dimethyl ether, also known as triglyme, is a member of the glycol ether family and is commonly used as a solvent in industries like electronics, pharmaceuticals, coatings, and more. Triglymes are chemically inert because they lack reactive functional groups, making them well-suited for chemical synthesis. They have strong solvating abilities and demonstrate excellent thermal and chemical stability, which makes them highly valuable as solvents and processing aids in the manufacturing and formulation of industrial chemicals.

Application

Triethylene glycol dimethyl ether can be used as a:
  • Extracting solvent in a modified SA-HPSW (Supercritical Anti-Solvent with High-Pressure Solvent Wash) system.
  • Solvent in the synthesis of passivated iron nanoparticles.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation markHealth hazard
GHS07,GHS08

Signal Word

Danger

Hazard Statements

H319 - H360Df

Hazard Classifications

Eye Irrit. 2 - Repr. 1B

Supplementary Hazards

EUH019

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

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Characterization of tetraethylene glycol passivated iron nanoparticles
da Silva Nunes E, et al.
Applied Surface Science, 315, 337-345 (2014)
H Liu et al.
Dalton transactions (Cambridge, England : 2003), 46(33), 10986-10995 (2017-08-05)
This work reports two new silver metalorganic precursors for the chemical vapor deposition of Ag metallic coatings. Both precursors are based on β-diketonate adducts, namely, Ag(hfac)(L) (H-hfac = 1,1,1,5,5,5-hexafluoro-2,4-pentanedione), where L is 1,10-phenanthroline (phen) or 2,5,8,11-tetraoxadodecane (triglyme). Using these ligands
Reproductive toxicology. Triethylene glycol dimethyl ether.
Environmental health perspectives, 105 Suppl 1, 239-240 (1997-02-01)
Dilek Cökeliler et al.
Dental materials : official publication of the Academy of Dental Materials, 23(3), 335-342 (2006-05-17)
This study evaluates the effect of plasma treated E-glass fiber to improve the mechanical properties of acrylic resin denture base material, polymethylmethacrlyate (PMMA). Plasma surface treatment of fibers is used as reinforcement in composite materials to modify the chemical and
J D George et al.
Fundamental and applied toxicology : official journal of the Society of Toxicology, 9(1), 173-181 (1987-07-01)
Triethylene glycol dimethyl ether (triEGdiME) is structurally related to several compounds which produce reproductive and developmental toxicity, including teratogenicity in laboratory animals. In the present study, triEGdiME (0, 250, 500, or 1000 mg/kg/day) was administered by gavage to timed-pregnant CD-1
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