04685
Nε-Methyl-L-lysine hydrochloride
≥98.0% (TLC)
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About This Item
Empirical Formula (Hill Notation):
C7H16N2O2 · HCl
CAS Number:
Molecular Weight:
196.68
EC Number:
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.32
Assay:
≥98.0% (TLC)
Quality Level
Assay
≥98.0% (TLC)
optical activity
[α]/D 20.5±1.5°, c = 0.1 in 1 M HCl
storage temp.
2-8°C
SMILES string
Cl.CNCCCC[C@H](N)C(O)=O
Cl.CNCCCC[C@H](N)C(O)=O
InChI
1S/C7H16N2O2.ClH/c1-9-5-3-2-4-6(8)7(10)11;/h6,9H,2-5,8H2,1H3,(H,10,11);1H/t6-;/m0./s1
InChI key
AQELUQTVJOFFBN-RGMNGODLSA-N
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Biochem/physiol Actions
N ε-methyl-L-lysine was identified as a lysine analog with inhibitory effects on the growth and sporulation of Penicillium chrysogenum and benzyl-penicillin formation by mycelia.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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A genetically encoded epsilon-N-methyl lysine in mammalian cells.
Dan Groff et al.
Chembiochem : a European journal of chemical biology, 11(8), 1066-1068 (2010-04-28)
M Moracci et al.
Enzyme and microbial technology, 17(11), 992-997 (1995-11-01)
The gene coding for the beta-glycosidase from the archaeon Sulfolobus solfataricus has been overexpressed in Escherichia coli. The enzyme was purified to homogeneity with a rapid purification procedure employing a thermal precipitation as a crucial step. The final yield was
M Friedman et al.
The Journal of nutrition, 111(8), 1362-1369 (1981-08-01)
Growth assays using mice on synthetic amino acid diets showed that substituting epsilon-N-methyl-L-lysine, epsilon-N-dimethyl-L-lysine and epsilon-N-trimethyl-L-lysine for lysine resulted in relative replacement values about 1/12, 1/20 and 1/25, respectively, of that obtained with the standard lysine diet. Similar studies showed
H Kalász et al.
Journal of chromatographic science, 43(4), 165-168 (2005-06-25)
Administration of (14)C-labelled L-deprenyl to rats results in the urinary elimination of a 14C-labelled compound. The 9-fluorenylmethoxycarbonyl chloride-reacted urine sample is fractionated by high-performance liquid chromatography (HPLC) on an octadecyl silica stationary phase. N(epsilon)-Monomethyl-lysine is identified in the fraction containing
F Zappacosta et al.
European journal of biochemistry, 222(3), 761-767 (1994-06-15)
Advanced mass spectrometric procedures have been extensively used to provide an accurate structural characterization of aspartate aminotransferase from Sulfolobus solfataricus. The amino acid sequence of this enzyme had previously been deduced from the DNA sequence. The accurate molecular mass of
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