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05160

β-Alanine

Name: β-Alanine
Brand: SIGMA

BioXtra, ≥99.0% (NT)

Synonym(s):

Beta-alanine, β-Ala, 3-Aminopropionic acid

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About This Item

Linear Formula:

NH₂CH₂CH₂COOH

CAS Number:

107-95-9

Molecular Weight:

89.09

PubChem Substance ID:

329747649

eCl@ss:

39030936

UNSPSC Code:

12352209

NACRES:

NA.26

EC Number:

203-536-5

MDL number:

MFCD00008200

Beilstein/REAXYS Number:

906793

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product line

BioXtra

Quality Level

300

assay

≥99.0% (NT)

form

crystals

ign. residue

≤0.1% (as SO₄)

loss

≤0.1% loss on drying, 20 °C (HV)

mp

~200 °C (dec.), 202 °C (dec.) (lit.)

anion traces

chloride (Cl^-): ≤50 mg/kg, sulfate (SO₄^2-): ≤50 mg/kg

cation traces

Mg: ≤5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Mn: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg

application(s)

peptide synthesis

InChI

1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6)

InChI key

UCMIRNVEIXFBKS-UHFFFAOYSA-N

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Related Categories

Amino Acids – Building Blocks of Life Science

Amino Acids, Resins & Reagents for Peptide Synthesis

Biochemicals

Cell Culture Supplements & Reagents

High-Purity Biochemicals and Reagents

Application

A new green approach to L-histidine and β-alanine analysis in dietary supplements using rapid and simple contactless conductivity detection integrated with high-resolution glass-microchip electrophoresis.: This paper presents a novel method for analyzing β-Alanine in dietary supplements, showcasing a green, efficient, and high-resolution technique (Pukleš et al., 2024).

Biochem/physiol Actions

Endogenous β-amino acid that is a nonselective agonist at glycine receptors and a ligand for the G protein-coupled orphan receptor, TGR7 (MrgD). β-Alanine is a component of pantothenic acid.

β-Alanine, a β amino acid, is a component of pantothenic acid and the rate limiting amino acid in the biosynthesis of the histidinyl antioxidant dipeptides carnosine and anserine.

β-Alanine, a β−amino acid, is a component of pantothenic acid and the rate-limiting amino acid in the biosynthesis of the histidinyl antioxidant dipeptides carnosine and anserine. Endogenous β-amino acid that is a nonselective agonist at glycine receptors and a ligand for the G protein-coupled orphan receptor, TGR7 (MrgD). β-Alanine flux plays a cytoprotective role by supporting the osmotic stability of marine organisms, preimplantation mouse embryos and mammalian cells exposed to hypoxic stress.

Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Simple enzymatic procedure for L-carnosine synthesis: whole-cell biocatalysis and efficient biocatalyst recycling.

Jan Heyland et al.

Microbial biotechnology, 3(1), 74-83 (2011-01-25)

β-Peptides and their derivates are usually stable to proteolysis and have an increased half-life compared with α-peptides. Recently, β-aminopeptidases were described as a new enzyme class that enabled the enzymatic degradation and formation of β-peptides. As an alternative to the

Role of beta-alanine supplementation on muscle carnosine and exercise performance.

Guilherme Giannini Artioli et al.

Medicine and science in sports and exercise, 42(6), 1162-1173 (2010-05-19)

In this narrative review, we present and discuss the current knowledge available on carnosine and beta-alanine metabolism as well as the effects of beta-alanine supplementation on exercise performance. Intramuscular acidosis has been attributed to be one of the main causes

Meta-analysis of randomized controlled trials on risk of myocardial infarction from the use of oral direct thrombin inhibitors.

Ramin Artang et al.

The American journal of cardiology, 112(12), 1973-1979 (2013-10-01)

Dabigatran has been associated with greater risk of myocardial infarction (MI) than warfarin. It is unknown whether the increased risk is unique to dabigatran, an adverse effect shared by other oral direct thrombin inhibitors (DTIs), or the result of a

Routine coagulation assays underestimate levels of antithrombin-dependent drugs but not of direct anticoagulant drugs in plasma from patients with cirrhosis.

Wilma Potze et al.

British journal of haematology, 163(5), 666-673 (2013-11-14)

There is increasing recognition that thrombotic complications may occur in patients with cirrhosis, and literature on antithrombotic treatment in these patients is rapidly emerging. Due to extensive haemostatic changes in patients with cirrhosis, careful monitoring of anticoagulant therapy may be

Stroke prevention in atrial fibrillation patients with chronic kidney disease.

Robert G Hart et al.

The Canadian journal of cardiology, 29(7 Suppl), S71-S78 (2013-06-29)

Chronic kidney disease (CKD) is prevalent in elderly patients with atrial fibrillation and is an independent risk factor for stroke. Warfarin anticoagulation is efficacious for stroke prevention in atrial fibrillation patients with moderate CKD (stage III, estimated glomerular filtration rate

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Global Trade Item Number

SKU	GTIN
05160-50G	04061838637185
05160-1KG	04061826714287
05160-250G	04061838637178

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