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Merck
CN

06840

Sigma-Aldrich

1-Methyltryptamine

≥95.0% (GC)

Synonym(s):

1-Methyl-1H-indole-3-ethanamine, 1-Methyl-3-(2-aminoethyl)indole, 2-(1-Methyl-1H-indol-3-yl)ethylamine, N1-Methyltryptamine, NMT

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About This Item

Empirical Formula (Hill Notation):
C11H14N2
CAS Number:
Molecular Weight:
174.24
Beilstein:
6874
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.25
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Quality Level

Assay

≥95.0% (GC)

form

liquid

color

light yellow

SMILES string

Cn1cc(CCN)c2ccccc12

InChI

1S/C11H14N2/c1-13-8-9(6-7-12)10-4-2-3-5-11(10)13/h2-5,8H,6-7,12H2,1H3

InChI key

CAAGZPJPCKMFBD-UHFFFAOYSA-N

Biochem/physiol Actions

Metabolite in N-methyltransferase metabolism of tryptamine and decarboxylation of 1-methyltryptophan.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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N-methylation of 1-methyltryptamines by indolethylamine N-methyltransferase.
R Lin et al.
Biochemical pharmacology, 24(11-12), 1239-1240 (1975-06-15)
E M Adkins et al.
Molecular pharmacology, 59(3), 514-523 (2001-02-17)
The serotonin (5-hydroxytryptamine, 5-HT) transporter (SERT) is responsible for the inactivation of synaptic 5-HT and is also a target for multiple psychostimulants. Despite the critical role of SERT in 5-HT inactivation and psychostimulant response, many aspects of the transporter's recognition

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