08161
2-Deoxy-L-ribonic acid lithium salt
≥95.0% (TLC)
Synonym(s):
2-Deoxy-L-erythro-pentonic acid lithium salt
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About This Item
Empirical Formula (Hill Notation):
C5H10O5 · xLi+
CAS Number:
Molecular Weight:
150.13 (free acid basis)
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.25
assay
≥95.0% (TLC)
optical activity
[α]/D -12.0±2.0°, 24 hr, c = 1 in 1 M HCl
storage temp.
2-8°C
SMILES string
OC[C@H](O)[C@H](O)CC(O)=O
InChI
1S/C5H10O5/c6-2-4(8)3(7)1-5(9)10/h3-4,6-8H,1-2H2,(H,9,10)/t3-,4+/m1/s1
InChI key
VBUWJOHKCBQXNU-DMTCNVIQSA-N
General description
L-Enantiomer of 2-deoxyribonic acid
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Yuichi Nakajima et al.
International journal of cancer, 119(7), 1710-1716 (2006-04-29)
Thymidine phosphorylase (TP), an enzyme involved in pyrimidine metabolism, is identical with an angiogenic factor, platelet-derived endothelial cell growth factor. 2-Deoxy-D-ribose (D-dRib), the degradation product of thymidine generated by TP activity, has been suggested to be a downstream mediator of
Constantine G Boojamra et al.
Bioorganic & medicinal chemistry letters, 18(3), 1120-1123 (2008-01-01)
GS-9148 (2'-Fd4AP, 4) has been identified as a nucleoside phosphonate reverse transcriptase (RT) inhibitor with activity against wild-type HIV (EC(50)=12 microM). Unlike many clinical RT inhibitors, relevant reverse transcriptase mutants (M184V, K65R, 6-TAMs) maintain a susceptibility to 2'-Fd4AP that is
Yuichi Nakajima et al.
Cancer research, 64(5), 1794-1801 (2004-03-05)
Thymidine phosphorylase (TP) catalyzes the reversible conversion of thymidine to thymine, thereby generating 2-deoxy-D-ribose-1-phosphate, which upon dephosphorylation forms 2-deoxy-D-ribose (D-dRib), a degradation product of thymidine. We have previously shown that D-dRib promotes angiogenesis and chemotaxis of endothelial cells and also
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 429058-1G | 04061825770970 |
| 429058-10G | 04061832100029 |
| 08161-10MG | 04061831598858 |
| 08161-50MG | 04061831598872 |
| 08161-250MG | 04061831598865 |