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Merck
CN

11700

Giemsa stain

Synonym(s):

Azure mixture sicc. Giemsa stain

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About This Item

Empirical Formula (Hill Notation):
C14H14ClN3S
CAS Number:
Molecular Weight:
291.80
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
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InChI

1S/C14H13N3S.ClH/c1-17(2)10-4-6-12-14(8-10)18-13-7-9(15)3-5-11(13)16-12;/h3-8,15H,1-2H3;1H

SMILES string

[Cl-].CN(C)c1ccc2N=C3C=CC(=[NH2+])C=C3Sc2c1

InChI key

NALREUIWICQLPS-UHFFFAOYSA-N

mp

300 °C (lit.)

suitability

suitable for microscopy

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Application

Giemsa stain has been used in a study to develop a fast and easy method for general fluorescent staining of cultured cells on transparent or opaque supports. Giemsa stain has also been used in a study to determine the cell block method using immunostaining for pancreatic juice cytology showed a much lower rate of equivocal borderline malignancy and a tendency for a higher diagnostic yield compared with smear cytology.

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Yutaka Noda et al.
Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 24(3), 168-174 (2012-04-18)
To elucidate the diagnostic efficacy of the cell block (CB) method by comparing it with that of conventional smear cytology for pancreatic juice obtained by endoscopic retrograde cholangiopancreatography (ERCP) in a randomized controlled trial fashion. A total of 170 patients
Kai Li et al.
Oncogene, 39(11), 2258-2274 (2019-12-14)
Previous studies have shown that the main function of VASP is to regulate the cytoskeleton and play an important role in promoting tumor cell metastasis. In this study, we first reveal that VASP is located in the nucleus of breast
Mollie Jurewicz et al.
Diabetes, 59(12), 3139-3147 (2010-09-16)
A number of clinical trials are underway to test whether mesenchymal stem cells (MSCs) are effective in treating various diseases, including type 1 diabetes. Although this cell therapy holds great promise, the optimal source of MSCs has yet to be
Rong-Xin Chen et al.
Journal of experimental & clinical cancer research : CR, 29, 172-172 (2010-12-31)
Specific gene expression is tightly regulated by various transcription factors. Osteopontin (OPN) is a phosphoprotein that mediates hepatocellular carcinoma (HCC) progression and metastasis. However, the mechanism of OPN up-regulation in HCC metastasis remains to be clarified. Oligonucleotide array-based transcription factor
Chun-Li Xiao et al.
BMC cancer, 11, 150-150 (2011-04-26)
Hepatocellular carcinoma (HCC) usually has a dismal prognosis because of its limited response to current pharmacotherapy and high metastatic rate. Sulfated oligosaccharide has been confirmed as having potent antitumor activities against solid tumors. Here, we explored the preclinical effects and

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