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14880

BIS-TRIS

Name: BIS-TRIS
Brand: SIGMA

BioXtra, ≥99.0% (NT)

Synonym(s):

2,2-Bis(hydroxymethyl)-2,2′,2″-nitrilotriethanol, 2-Bis(2-hydroxyethyl)amino-2-(hydroxymethyl)-1,3-propanediol, Bis(2-hydroxyethyl)amino-tris(hydroxymethyl)methane

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About This Item

Empirical Formula (Hill Notation):

C₈H₁₉NO₅

CAS Number:

6976-37-0

Molecular Weight:

209.24

EC Number:

230-237-7

UNSPSC Code:

12161700

PubChem Substance ID:

329750647

Beilstein/REAXYS Number:

2205275

MDL number:

MFCD00002853

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product line

BioXtra

assay

≥99.0% (NT)

ign. residue

≤0.3%

loss

≤1% loss on drying, 20 °C (HV)

useful pH range

5.8-7.2

pKa (25 °C)

6.5

mp

102-105 °C

solubility

H₂O: 0.2 g/mL at 20 °C, clear

anion traces

chloride (Cl^-): ≤50 mg/kg, sulfate (SO₄^2-): ≤50 mg/kg

cation traces

Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg

SMILES string

OCCN(CCO)C(CO)(CO)CO

InChI

1S/C8H19NO5/c10-3-1-9(2-4-11)8(5-12,6-13)7-14/h10-14H,1-7H2

InChI key

OWMVSZAMULFTJU-UHFFFAOYSA-N

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pictograms

GHS07

signalword

Warning

hcodes

H319

pcodes

P264 - P280 - P305 + P351 + P338 - P337 + P313

Hazard Classifications

Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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The purified myxoma virus gamma interferon receptor homolog M-T7 interacts with the heparin-binding domains of chemokines.

A S Lalani et al.

Journal of virology, 71(6), 4356-4363 (1997-06-01)

The myxoma virus T7 protein M-T7 is a functional soluble gamma interferon receptor homolog that has previously been shown to bind gamma interferon and inhibit its antiviral activities in a species-specific manner, but gene knockout analysis has suggested a further

Hemoglobin degradation in the human malaria pathogen Plasmodium falciparum: a catabolic pathway initiated by a specific aspartic protease.

D E Goldberg et al.

The Journal of experimental medicine, 173(4), 961-969 (1991-04-01)

Hemoglobin is an important nutrient source for intraerythrocytic malaria organisms. Its catabolism occurs in an acidic digestive vacuole. Our previous studies suggested that an aspartic protease plays a key role in the degradative process. We have now isolated this enzyme

Genetic mapping of a mutation that causes ribonucleases III deficiency in Escherichia coli.

F W Studier

Journal of bacteriology, 124(1), 307-316 (1975-10-01)

the mutation that causes ribonuclease III (RNase III) deficiency in strain AB301-105 of Kindler et al. (1973) has been mapped by use of F' merodiploids, Hfr matings, and P1 transduction. This mutation, rnc-105, lies close to nadB, near 49 min

Effect of membrane charge on flow and protein transport during ultrafiltration.

Amit Mehta et al.

Biotechnology progress, 22(2), 484-492 (2006-04-08)

Although several recent studies have demonstrated the importance of electrostatic interactions in ultrafiltration, there have been few quantitative studies of the effects of membrane charge density on protein transport and membrane hydraulic permeability. Data were obtained using a series of

Characterization and deep sequencing analysis of exosomal and non-exosomal miRNA in human urine.

Lesley Cheng et al.

Kidney international, 86(2), 433-444 (2013-12-20)

Micro RNAs (miRNAs) have been shown to circulate in biological fluids and are enclosed in vesicles such as exosomes; they are present in urine and represent a noninvasive methodology to detect biomarkers for diagnostic testing. The low abundance of RNA

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Global Trade Item Number

SKU	GTIN
348554-100ML	04061837640124

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