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Merck
CN

15794

Coumarin 466

BioReagent, suitable for fluorescence, ≥98.0% (HPLC)

Synonym(s):

7-(Diethylamino)coumarin

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About This Item

Empirical Formula (Hill Notation):
C13H15NO2
CAS Number:
Molecular Weight:
217.26
EC Number:
243-888-7
UNSPSC Code:
12161900
PubChem Substance ID:
Beilstein/REAXYS Number:
3609055
MDL number:
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InChI key

QXAMGWKESXGGNV-UHFFFAOYSA-N

InChI

1S/C13H15NO2/c1-3-14(4-2)11-7-5-10-6-8-13(15)16-12(10)9-11/h5-9H,3-4H2,1-2H3

SMILES string

CCN(CC)c1ccc2C=CC(=O)Oc2c1

product line

BioReagent

assay

≥98.0% (HPLC)

form

solid

fluorescence

λex 380 nm; λem 460 nm in methanol

suitability

suitable for fluorescence

storage temp.

2-8°C

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Doroty Codoni et al.
International journal of pharmaceutics, 496(2), 1015-1025 (2015-11-05)
Disc-shaped nanoparticles with high aspect ratios have been reported to show preferential cellular uptake in vitro by mammalian cells. However, engineering and producing such disc-shaped nanoparticles are often complex. This study reports for the first time the use of a
Pradip Nirbhavane et al.
AAPS PharmSciTech, 18(3), 829-837 (2016-06-29)
Rifabutin (RFB) is prescribed for the treatment of tuberculosis infections as well as Mycobacterium avium complex (MAC) infection in immunocompromised individuals and HIV patients. With a view to develop a sustained release oral solid lipid nanoformulation (SLN), RFB was encapsulated
Sudeep Sudesh Pukale et al.
Acta biomaterialia, 115, 393-409 (2020-08-28)
Lipid-polymer hybrid nanoparticles (LPNs) exhibit several advantages over polymeric and non-polymeric systems in terms of improved drug loading, controlled release, stability, and cellular uptake. Herein we report a scalable and stable monolithic lipid-polymer hybrid nanoparticles (LPNs) consisting of a combination
Yusuf Haggag et al.
Drug delivery and translational research, 10(5), 1353-1366 (2020-04-03)
Poly(lactic-co-glycolic acid) nanocapsules containing amphiphilic biosurfactant sophorolipids were formulated using a dispersion-based procedure. Di-block copolymers were used to vary peripheral poly(ethylene glycol) density, and variation in the oil core was used to achieve efficient encapsulation of the sophorolipid payload. Particulate

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