16513
Ethyl 4-[(3-amino-2-naphthyl)aminomethyl]benzoate hydrochloride
suitable for fluorescence, ≥99.0% (HPLC)
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About This Item
Empirical Formula (Hill Notation):
C20H20N2O2 · HCl
Molecular Weight:
356.85
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
InChI
1S/C20H20N2O2.ClH/c1-2-24-20(23)15-9-7-14(8-10-15)13-22-19-12-17-6-4-3-5-16(17)11-18(19)21;/h3-12,22H,2,13,21H2,1H3;1H
SMILES string
Cl[H].CCOC(=O)c1ccc(CNc2cc3ccccc3cc2N)cc1
InChI key
IMTHVIIBTLZVBZ-UHFFFAOYSA-N
assay
≥99.0% (HPLC)
suitability
in accordance for fluorescence, suitable for fluorescence
Application
Ethyl 4-[(3-amino-2-naphthyl)aminomethyl]benzoate hydrochloride (DAN-1 EE), a membrane permeable ester of DAN-1, is used as a fluorescent indicator (sensor dye) for bioimaging of nitric oxide within cells in vivo.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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H Kojima et al.
Biological & pharmaceutical bulletin, 20(12), 1229-1232 (1998-02-03)
Nitric oxide (NO) has been reported to play various roles as a signal transmitter. However, detailed functions of NO have yet to be clarified. We have developed a fluorescent indicator for NO imaging in living cells. The N-nitrosation of newly
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