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Merck
CN

16513

Sigma-Aldrich

Ethyl 4-[(3-amino-2-naphthyl)aminomethyl]benzoate hydrochloride

suitable for fluorescence, ≥99.0% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C20H20N2O2 · HCl
Molecular Weight:
356.85
MDL number:
MFCD04972009
UNSPSC Code:
12352200
PubChem Substance ID:
57647574

Key Documents

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Assay

≥99.0% (HPLC)

suitability

in accordance for fluorescence
suitable for fluorescence

SMILES string

Cl[H].CCOC(=O)c1ccc(CNc2cc3ccccc3cc2N)cc1

InChI

1S/C20H20N2O2.ClH/c1-2-24-20(23)15-9-7-14(8-10-15)13-22-19-12-17-6-4-3-5-16(17)11-18(19)21;/h3-12,22H,2,13,21H2,1H3;1H

InChI key

IMTHVIIBTLZVBZ-UHFFFAOYSA-N

Application

Ethyl 4-[(3-amino-2-naphthyl)aminomethyl]benzoate hydrochloride (DAN-1 EE), a membrane permeable ester of DAN-1, is used as a fluorescent indicator (sensor dye) for bioimaging of nitric oxide within cells in vivo.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCBH5630V
1268517

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H Kojima et al.
Biological & pharmaceutical bulletin, 20(12), 1229-1232 (1998-02-03)
Nitric oxide (NO) has been reported to play various roles as a signal transmitter. However, detailed functions of NO have yet to be clarified. We have developed a fluorescent indicator for NO imaging in living cells. The N-nitrosation of newly

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