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Merck
CN

22040

β-Carotene

≥97.0% (UV)

Synonym(s):

β,β-Carotene, Provitamin A

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About This Item

Empirical Formula (Hill Notation):
C40H56
CAS Number:
Molecular Weight:
536.87
UNSPSC Code:
12352200
NACRES:
SB.54
PubChem Substance ID:
EC Number:
230-636-6
Beilstein/REAXYS Number:
1917416
MDL number:
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biological source

synthetic

assay

≥97.0% (UV)

form

powder

technique(s)

HPLC: suitable

impurities

≤0.001% heavy metals

loss

≤0.2% loss on drying

color

red to dark red

mp

176-184 °C (dec.)

solubility

chloroform: 10 mg/mL, clear, dark orange-red

shipped in

dry ice

storage temp.

2-8°C

SMILES string

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)CCCC2(C)C)C(C)(C)CCC1

InChI

1S/C40H56/c1-31(19-13-21-33(3)25-27-37-35(5)23-15-29-39(37,7)8)17-11-12-18-32(2)20-14-22-34(4)26-28-38-36(6)24-16-30-40(38,9)10/h11-14,17-22,25-28H,15-16,23-24,29-30H2,1-10H3/b12-11+,19-13+,20-14+,27-25+,28-26+,31-17+,32-18+,33-21+,34-22+

InChI key

OENHQHLEOONYIE-JLTXGRSLSA-N

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Application

  • β-Carotene has been used as a standard to measure β-carotene levels in plasma samples via HPLC (high performance liquid chromatography).
  • It has been used to study the effects of vitamins on growth of Mycobacteria in radiometric culture.
  • It has been used as a supplement in the growth medium of Drosophila melanogaster to allow intake of vitamin A.

Biochem/physiol Actions

The most important of the provitamins A, β-carotene can be classified as an antioxidant due to its inhibition of radical initiated peroxidation in vitro. However, in vivo it appears to act either as an antioxidant or a prooxidant depending on cellular environment. It reduces the incidence of many cancers, but enhances lung cancer incidence in smokers.
The most important of the provitamins A.

Other Notes

As a probe of lipid domains of reconstituted human plasma low-density lipoprotein

Disclaimer

Purchase minimum quantity required. Discard one month after opening.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

217.9 °F - closed cup

flash_point_c

103.3 °C - closed cup

ppe

Eyeshields, Gloves


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G C Chen et al.
Biochemistry, 19(20), 4706-4712 (1980-09-30)
Mixtures of neutral lipids containing cholesteryl esters and beta-carotene were used to reconstitute the lipid core of heptane-extracted low-density lipoproteins (LDL). The resulting preparations of reconstituted LDL, referred to as r-[cholesteryl ester + beta-carotene]LDL, exhibited temperature-dependent circular dichroism (CD) in
Lack of Dietary Polyunsaturated Fatty Acids Causes Synapse Dysfunction in the Drosophila Visual System.
Ziegler AB, et al.
PLoS ONE, 10, e0135353-e0135353 (2015)
Vitamins A & D inhibit the growth of mycobacteria in radiometric culture.
Greenstein RJ, et al.
PLoS ONE, 7, e29631-e29631 (2012)
Kyeongjin Kim et al.
Experimental & molecular medicine, 41(6), 429-439 (2009-03-27)
Small heterodimer partner (SHP) is an atypical member of nuclear receptor superfamily that lacks a DNA-binding domain. In previous study, we showed that SHP, c-jun, p65 of NF-gammaB subunits, and p21WAF1 expression was increased during monocytic differentiaton with the exposure
Antonio Molino et al.
Molecules (Basel, Switzerland), 24(4) (2019-02-24)
Microalgae Dunaliella salina contains useful molecules such as β-carotene and fatty acids (FAs), which are considered high value-added compounds. To extract these molecules, supercritical carbon dioxide was used at different operative conditions. The effects of mechanical pre-treatment (grinding speed at

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Global Trade Item Number

SKUGTIN
22040-1G-F04061835541119
22040-5G-F04061835515417

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