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Merck
CN

26421

Sodium stearate

≥88% fatty acids (as stearic acid) basis, powder

Synonym(s):

Octadecanoic acid sodium salt, Stearic acid sodium salt

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About This Item

Linear Formula:
CH3(CH2)16COONa
CAS Number:
822-16-2
Molecular Weight:
306.46
EC Number:
212-490-5
UNSPSC Code:
12352211
PubChem Substance ID:
57648172
Beilstein/REAXYS Number:
3576813
MDL number:
MFCD00036404

Key Documents

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InChI key

RYYKJJJTJZKILX-UHFFFAOYSA-M

InChI

1S/C18H36O2.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h2-17H2,1H3,(H,19,20);/q;+1/p-1

SMILES string

[Na+].CCCCCCCCCCCCCCCCCC([O-])=O

assay

≥88% fatty acids (as stearic acid) basis

form

powder

impurities

≤0.2% free alkali (as NaOH), ≤8% Na

loss

≤2.5% loss on drying, 105 °C

lipid type

fatty acid modified lipids

Quality Level

100

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Biochem/physiol Actions

Stearic acid induces ER stress and cell death via effects on ER luminal calcium stores in H4IIE liver cells and primary hepatocytes .

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCBW2870
BCBW2869
BCBW2868
BCBV6146
BCBS9700V

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Solvent-induced crystal morphology transformation in a ternary soap system: sodium stearate crystalline fibers and platelets.
Liang J, et al.
Langmuir, 17(21), 6447-6454 (2001)
Chiara Parlati et al.
Pharmaceutical research, 26(5), 1084-1092 (2009-02-03)
Tobramycin microparticulate powders containing the hydrophobic adjunct sodium stearate were studied for their use as pulmonary formulations in dry powder inhalers. Spray-dried powders were characterized in terms of particle size distribution, morphology, crystallinity, drug dissolution rate, toxicity on epithelial lung
A Phase Rule Study of the System Sodium Stearate-Water.
McBain JW, et al.
The Journal of Physical Chemistry, 44(9), 1013-1024 (1940)
Sodium stearate-catalyzed multicomponent reactions for efficient synthesis of spirooxindoles in aqueous micellar media.
Wang L-M, et al.
Tetrahedron, 66(1), 339-343 (2010)
Yuren Wei et al.
Molecular and cellular biochemistry, 331(1-2), 31-40 (2009-05-16)
Chronic exposure to elevated free fatty acids, in particular long chain saturated fatty acids, provokes endoplasmic reticulum (ER) stress and cell death in a number of cell types. The perturbations to the ER that instigate ER stress and activation of
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