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Merck
CN

268A-1

Sigma-Aldrich

IgD Rabbit Polyclonal Antibody

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

Key Documents

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biological source

rabbit

Quality Level

100
500

conjugate

unconjugated

antibody form

Ig fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (268A-14)
vial of 0.5 mL concentrate (268A-15)
bottle of 1.0 mL predilute (268A-17)
vial of 1.0 mL concentrate (268A-16)
bottle of 7.0 mL predilute (268A-18)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

control

tonsil

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

Related Categories

General description

Anti-IgD antibody reacts with surface immunoglobulin IgD delta chains. This antibody is useful when identifying leukemias, plasmacytomas, and B-cell lineage derived lymphomas (in particular Marginal Zone Lymphoma). Cytoplasmic staining is easily identified on paraffin tissue. Surface immunoglobulin is difficult to demonstrate on paraffin sections but can be demonstrated on frozen sections.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note


IVD
IVD
IVD
RUO

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
IgD (polyclonal) Positive Control Slides, Product No. 268S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
0000430348
0000430348
0000414976
0000414976
0000407829

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M Mollejo et al.
The American journal of surgical pathology, 21(7), 772-780 (1997-07-01)
Splenic marginal zone lymphoma (SMZL) has recently been proposed as a distinctive type of low-grade B-cell lymphoma. Although there is general agreement that this entity exists, its precise definition is blurred by uncertainty in differential diagnosis from other low-grade B-cell
M Bertero et al.
Journal of the American Academy of Dermatology, 30(1), 23-30 (1994-01-01)
Mantle zone lymphoma (MZL) is a B-cell proliferation regarded as the follicular variant of intermediate lymphocytic lymphoma (ILL). Neoplastic small lymphoid cells proliferate as wide mantles around atrophic centers of benign appearance. The clinical, histologic, and immunohistochemical features of four
D Gupta et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 13(11), 1161-1166 (2000-12-06)
Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) typically involves nodal or extranodal tissues as a diffuse proliferation with pseudofollicular growth centers obliterating normal architecture. We describe 16 cases of CLL/SLL in which the neoplasm was confined to the marginal zone, perifollicular
K Oka et al.
Acta haematologica, 90(2), 84-89 (1993-01-01)
Biopsy specimens obtained from 2 patients with monocytoid B cell lymphoma, 7 with mantle zone lymphoma, 7 with small lymphocytic lymphoma or B chronic lymphocytic leukemia, and 6 with hairy cell leukemia were investigated using an immunohistochemical method to detect
E Campo et al.
The American journal of surgical pathology, 23(1), 59-68 (1999-01-15)
The existence of primary nodal marginal zone lymphomas (MZL) is controversial, as is their relationship to putative extranodal counterparts. Most nodal lymphomas with monocytoid B cell/marginal zone differentiation exhibit the morphologic and immunophenotypical characteristics of extranodal MALT-lymphomas. Splenic marginal zone
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