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Merck
CN

268A-1

IgD Rabbit Polyclonal Antibody

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Technical Service
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Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

biological source

rabbit

conjugate

unconjugated

antibody form

Ig fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (268A-14)
vial of 0.5 mL concentrate (268A-15)
bottle of 1.0 mL predilute (268A-17)
vial of 1.0 mL concentrate (268A-16)
bottle of 7.0 mL predilute (268A-18)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

control

tonsil

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

Quality Level

Analysis Note


IVD

IVD

IVD

RUO

General description

Anti-IgD antibody reacts with surface immunoglobulin IgD delta chains. This antibody is useful when identifying leukemias, plasmacytomas, and B-cell lineage derived lymphomas (in particular Marginal Zone Lymphoma). Cytoplasmic staining is easily identified on paraffin tissue. Surface immunoglobulin is difficult to demonstrate on paraffin sections but can be demonstrated on frozen sections.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
IgD (polyclonal) Positive Control Slides, Product No. 268S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Regulatory Information

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M Bertero et al.
Journal of the American Academy of Dermatology, 30(1), 23-30 (1994-01-01)
Mantle zone lymphoma (MZL) is a B-cell proliferation regarded as the follicular variant of intermediate lymphocytic lymphoma (ILL). Neoplastic small lymphoid cells proliferate as wide mantles around atrophic centers of benign appearance. The clinical, histologic, and immunohistochemical features of four
M Mollejo et al.
The American journal of surgical pathology, 21(7), 772-780 (1997-07-01)
Splenic marginal zone lymphoma (SMZL) has recently been proposed as a distinctive type of low-grade B-cell lymphoma. Although there is general agreement that this entity exists, its precise definition is blurred by uncertainty in differential diagnosis from other low-grade B-cell
E Campo et al.
The American journal of surgical pathology, 23(1), 59-68 (1999-01-15)
The existence of primary nodal marginal zone lymphomas (MZL) is controversial, as is their relationship to putative extranodal counterparts. Most nodal lymphomas with monocytoid B cell/marginal zone differentiation exhibit the morphologic and immunophenotypical characteristics of extranodal MALT-lymphomas. Splenic marginal zone
I Anagnostopoulos et al.
Histopathology, 39(6), 561-565 (2002-03-21)
We report a case of mantle cell lymphoma masquerading as a marginal zone cell lymphoma. In the initial manifestation in the palatine tonsils, the neoplastic cells were found to grow exclusively within the marginal zones of secondary follicles which showed
S Mori et al.
Acta pathologica japonica, 36(10), 1429-1440 (1986-10-01)
Expression of IgD was studied immunopathologically on 50 cases of B cell lymphomas (B MLs), together with various B cell markers including IgM, kappa and lambda chains, B1, B2, (OK)B2, (OB)B7, (OK)T10, NUB1, Leu 1, Leu 14, and PCA. IgD

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