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Merck
CN

27597

Coenzyme Q9

≥96.0% (HPLC)

Synonym(s):

Q-9, Ubiquinone-45, Ubiquinone-9

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About This Item

Empirical Formula (Hill Notation):
C54H82O4
CAS Number:
303-97-9
Molecular Weight:
795.23
UNSPSC Code:
12352204
NACRES:
NA.51
PubChem Substance ID:
57648260
MDL number:
MFCD00056635
Beilstein/REAXYS Number:
1900081

Key Documents

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Product Name

Coenzyme Q9, ≥96.0% (HPLC)

InChI

1S/C54H82O4/c1-40(2)22-14-23-41(3)24-15-25-42(4)26-16-27-43(5)28-17-29-44(6)30-18-31-45(7)32-19-33-46(8)34-20-35-47(9)36-21-37-48(10)38-39-50-49(11)51(55)53(57-12)54(58-13)52(50)56/h22,24,26,28,30,32,34,36,38H,14-21,23,25,27,29,31,33,35,37,39H2,1-13H3/b41-24+,42-26+,43-28+,44-30+,45-32+,46-34+,47-36+,48-38+

SMILES string

COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(\C)C)=C(C)C1=O

InChI key

UUGXJSBPSRROMU-WJNLUYJISA-N

assay

≥96.0% (HPLC)

form

powder

application(s)

cell analysis

storage temp.

−20°C

Quality Level

100

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Related Categories

Application

Coenzyme Q9 (Ubiquinone-9; Ubi-9) may be used in the study of ubiquinones in vivo and in vitro. Coenzyme Q9 may be used as a reference compound in analytic procedures that monitor specific ubiquinone levels under various physiological and pathological conditions and in food-stocks.
Coenzyme Q9 has been used to investigate its interference in the detection of coenzyme Q10 (CoQ10) by fluorescent spectrophotometer (FS-ECA). It has also been used as an analyte in chromatographic analysis of different biological samples that correspond to different genetic conditions.

Biochem/physiol Actions

The coenzyme Q (CoQ) can perform multiple functions such as electron and proton transport. CoQ9 performs similar functions to CoQ10 as the native CoQ in Caenorhabditis elegans. CoQ9 as well as other CoQ molecules may have an impact on cell life-span and these molecules are seeing increase usage in such studies.

General description

Coenzyme Q9 (Ubiquinone-9; Ubi-9) is a 9 isoprenyl group member of a family of ubiquinones that share a quinine chemical group but differ in the number of isoprenyl chemical subunits in their tail. The CoQ compounds are lipid soluble components of cell membranes.

Other Notes

An efficient electron and proton translocator in liposome systems; Prevents the appearance of adriamycin®-associated cardiotoxic phenomena in mice and rabbits.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Legal Information

Adriamycin is a registered trademark of RDF Pharmacia & Upjohn S.P.A.

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
268147/1

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Lidiya Bebrevska et al.
Journal of ethnopharmacology, 127(1), 112-117 (2009-10-06)
Oxidative stress has been associated with many pathological disorders such as atherosclerosis, diabetes and cancer. Supplementation with exogenous antioxidants, including phenolic compounds from plant sources, may help to restore the pro-oxidative/antioxidative balance. To take into account effects of absorption, metabolisation
G. Hauska
Dev. Bioenerg. Biomembr., 1, 177-177 (1977)
A rapid and non-invasive fluorescence method for quantifying coenzyme Q10 in blood and urine in clinical analysis
Fei X, et al.
Journal of Clinical Laboratory Analysis, e23130-e23130 (2019)
Rohit Kohli et al.
Hepatology (Baltimore, Md.), 52(3), 934-944 (2010-07-08)
Diets high in saturated fat and fructose have been implicated in the development of obesity and nonalcoholic steatohepatitis (NASH) in humans. We hypothesized that mice exposed to a similar diet would develop NASH with fibrosis associated with increased hepatic oxidative
Adriamycin associated cardiotoxicity: research on prevention with coenzyme Q.
C Bertazzoli et al.
Pharmacological research communications, 9(3), 235-250 (1977-03-01)
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