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Merck
CN

279M-1

Macrophage (HAM-56) Mouse Monoclonal Antibody

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352202
Conjugate:
unconjugated
Clone:
HAM-56, monoclonal
Application:
IHC (p)
Citations:
4

Key Documents

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biological source

mouse

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

HAM-56, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (279M-14), vial of 0.5 mL concentrate (279M-15), bottle of 1.0 mL predilute (279M-17), vial of 1.0 mL concentrate (279M-16), bottle of 7.0 mL predilute (279M-18)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

isotype

IgMκ

control

tonsil

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

General description

Anti-HAM-56 reacts with tingible macrophages, interdigitating macrophages of lymph nodes and tissue macrophages, e.g. Kupffer cells of the liver and alveolar macrophages of the lung. The antibody also stains a subpopulation of endothelial cells, most prominently those of the capillaries and smaller blood vessels. Anti-HAM-56 antibody reacts with monocytes, but is unreactive with B and T-lymphocytes.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note


IVD
IVD
IVD
RUO

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Macrophage Positive Control Slides, Product No. 279S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

监管及禁止进口产品
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Certificates of Analysis (COA)

Lot/Batch Number
0000125713
0000120273
0000106395
0000106394
0000086211

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C Bosman et al.
Journal of pediatric hematology/oncology, 21(1), 31-37 (1999-02-25)
The phenotype of the proliferating cells in two patients with erythrophagocytic histiocytosis is described. These 6- and 18-month-old female patients presented with fever, anemia, hepatosplenomegaly, and lymphadenopathy. Clinical histories were reviewed, and pathological specimens of both patients were studied by
C E Alpers et al.
American journal of clinical pathology, 92(5), 662-665 (1989-11-01)
The histogenesis of the multinucleated cells that characterize myeloma cast nephropathy ("myeloma kidney") has long been a subject of debate. Recent studies have implicated monocyte/macrophage-derived cells rather than tubular epithelial cells as the progenitors of these multinucleated cells. In this
Y Soini et al.
Pathology, research and practice, 186(6), 759-767 (1990-12-01)
Nine cases of malignant fibrous histiocytomas (MFH) were examined immunohistochemically in frozen sections with six different monoclonal antibodies to histiomonocytic and related cells (EBM11, HAM-56, KB90, antibodies to dendritic reticulum cells, HLADR and LCA). Ten other soft tissue sarcomas, two
A M Gown et al.
The American journal of pathology, 125(1), 191-207 (1986-10-01)
The authors have performed immunocytochemical investigations of the distribution of various cell types in human atherosclerotic plaques using monoclonal antibodies specific to smooth muscle cells (CGA7 [Gown et al, J Cell Biol 1985, 100:807-813] and HHF35 [Tsukada et al, Am

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