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Merck
CN

30957

2-Deoxy-D-ribono-1,4-lactone

≥95% (GC)

Synonym(s):

(4S,5R)-4-Hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one, 2-Deoxy-D-ribonic acid γ-lactone

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About This Item

Empirical Formula (Hill Notation):
C5H8O4
CAS Number:
Molecular Weight:
132.11
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
81260
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assay

≥95% (GC)

optical activity

[α]/D 19.0±2.5°, c = 1 in H2O

suitability

conforms to structure for Proton NMR spectrum

storage temp.

−20°C

SMILES string

O[C@H]1CC(O[C@@H]1CO)=O

InChI

1S/C5H8O4/c6-2-4-3(7)1-5(8)9-4/h3-4,6-7H,1-2H2/t3-,4+/m0/s1

InChI key

YIXDEYPPAGPYDP-IUYQGCFVSA-N



Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Haidong Huang et al.
Journal of the American Chemical Society, 130(19), 6080-6081 (2008-04-17)
The ability of DNA polymerases to maintain the integrity of the genome even after it has been structurally altered is vital. There is considerable interest in determining the structural properties of the DNA template that polymerases recognize when determining which
Water-soluble constituents of fennel. IX. Glucides and nucleosides.
Kitajima, J., et al.
Chemical & Pharmaceutical Bulletin, 47, 988-992 (1999)
Haidong Huang et al.
The Journal of organic chemistry, 73(7), 2695-2703 (2008-03-08)
DNA damage results in the formation of abasic sites from the formal hydrolysis of the glycosidic bond (AP) and several oxidized abasic lesions. Previous studies on AP sites revealed that DNA polymerases preferentially incorporated dA opposite them in approximately 80%