31149
Deoxyribonucleic acid, low molecular weight from salmon sperm
Synonym(s):
Salmon sperm dsDNA, low molecular weight DNA, DNA
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About This Item
CAS Number:
UNSPSC Code:
41106310
eCl@ss:
32160414
EC Number:
309-566-6
NACRES:
NA.52
MDL number:
Biological source:
fish
Form:
lyophilized powder
Solubility:
50 mM Tris pH 8.0: 10 mg/mL, clear, faintly brown-yellow
Storage temp.:
2-8°C
biological source
fish
grade
Molecular Biology, puriss. p.a.
form
lyophilized powder
impurities
≤5% protein
solubility
50 mM Tris pH 8.0: 10 mg/mL, clear, faintly brown-yellow
absorbance ratio
A260/280 nm ~1.4
storage temp.
2-8°C
Application
Various concentrations of Deoxyribonucleic acid, low molecular weight, from salmon sperm has been used:
- to study DNA binding to silicon-substituted hydroxyapatite nanocrystals.
- in simple electrochemical DNA biosensors to detect and evaluate DNA damage caused by UV-C radiation and reactive oxygen species.
- as a precursor in the synthesis of the bio-dots.
Biochem/physiol Actions
Salmon sperm DNA is often used as a blocking agent invarious research applications. It isknown to improve the specificity and sensitivity of the multi-AP assay byreducing non-specific binding and background signal.
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
动植物源性产品
低风险生物材料
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Eiji Sunami et al.
Clinical chemistry, 55(3), 559-567 (2009-01-10)
Prostate cancer (PCa) detection using serum-based prostate specific antigen (PSA) is limited by frequent false-positive and -negative results. Genetic aberrations such as allelic imbalance (AI) and epigenetic changes such as promoter hypermethylation have been detected in circulating DNA of cancer
J J Gao et al.
Journal of immunology (Baltimore, Md. : 1950), 166(11), 6855-6860 (2001-05-22)
LPS is well recognized for its potent capacity to activate mouse macrophages to produce TNF-alpha, an important inflammatory mediator in bacterial infection-related diseases such as septic shock. We demonstrate here that while inducing only low levels of TNF-alpha alone, DNA
Thiol modification of silicon-substituted hydroxyapatite nanocrystals facilitates fluorescent labelling and visualisation of cellular internalisation
Williams RL et al
Journal of Material Chemistry B: Materials for Biology and Medicine, 35, 4370-4378 (2013)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 31149-10G-F | 04061826681626 |
| 31149-50G-F | 04061826681633 |