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Merck
CN

32856

May-Grünwald solution

according to May-Grünwald

Synonym(s):

Eosin – methylene blue solution, Eosin methylene blue according to May-Grünwald

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About This Item

UNSPSC Code:
12171500
PubChem Substance ID:
329754362
EC Number:
200-659-6
MDL number:
MFCD00005038

Key Documents

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InChI key

NXBZXYJXNIFCRJ-UHFFFAOYSA-M

InChI

1S/C21H10Br4O5.K/c1-29-21(28)9-5-3-2-4-8(9)14-10-6-12(22)17(26)15(24)19(10)30-20-11(14)7-13(23)18(27)16(20)25;/h2-7,26H,1H3;/q;+1/p-1

SMILES string

[K+].COC(=O)c1ccccc1C2=C3C=C(Br)C(=O)C(Br)=C3Oc4c(Br)c([O-])c(Br)cc24

quality

according to May-Grünwald

suitability

passes test for UV spectrum

General description

May-Grünwald-Giemsa (MGG) stain is a Romanowsky-type, polychromatic stain as those of Giemsa, Leishman and Wright. It is used as reference stain in haematology. It is also used as routine stain in diagnostic cytopathology for the study of air-dried preparations (centrifuged body fluids, lymph node imprints, and fine needle aspirations).

Application

May-Grünwald and Giemsa stain was used for staining polymorphonuclear cells, monocytes and lymphocytes, for differential leukocyte counts, during hematological analysis, in an experimental study conducted to study immune responses in the pathology of acute magnesium deficiency in rats. It was also used to stain cells from bronchoalveolar lavage (BAL) fluid, in an experimental investigation, done to study the role of Fas ligand in murine silicosis.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

53.6 °F

flash_point_c

12 °C

ppe

Eyeshields, Faceshields, Gloves

Regulatory Information

危险化学品
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Certificates of Analysis (COA)

Lot/Batch Number
SZBE0800V
SZBC328BV
SZBC328B
SZBC075CV
SZBC075C

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Inflammatory response following acute magnesium deficiency in the rat.
Malpuech BC
Biochim. Biophys. Acta Gen. Subj., 1501 (2), 91-98 (2000)
Eric Piaton et al.
Annales de pathologie, 35(4), 294-305 (2015-07-21)
May-Grünwald-Giemsa (MGG) stain is a Romanowsky-type, polychromatic stain as those of Giemsa, Leishman and Wright. Apart being the reference method of haematology, it has become a routine stain of diagnostic cytopathology for the study of air-dried preparations (lymph node imprints
Fas ligand triggers pulmonary silicosis.
Borges VM
The Journal of Experimental Medicine, 194 (2), 155-164 (2001)
Young-Whan Choi et al.
Journal of ethnopharmacology, 178, 17-24 (2015-12-18)
The giant butterbur Petasites japonicus is used to treat asthma and allergic diseases in traditional Korean, Japanese, and Chinese medicine. To elucidate the anti-allergic effect of Petasites genus, we studied effects of several compounds from Petasites japonicus leaves and found
Mi-Jeong Kim et al.
European journal of pharmacology, 852, 25-33 (2019-02-25)
The effects of candesartan and irbesartan, antagonists of the type I angiotensin II receptor, were investigated on allergic asthma. The antigen-induced degranulation was measured by evaluating β-hexosaminidase activity in vitro. Additionally, a murine ovalbumin-induced allergic asthma model was used to
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