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Merck
CN

38216

N-[4-(5,6-Dimethoxy-N-phthalimidinyl)phenyl]maleimide

≥97.0% (HPLC)

Synonym(s):

DPM

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About This Item

Empirical Formula (Hill Notation):
C20H16N2O5
CAS Number:
Molecular Weight:
364.35
PubChem Substance ID:
UNSPSC Code:
12352200
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assay

≥97.0% (HPLC)

SMILES string

COc1cc2CN(C(=O)c2cc1OC)c3ccc(cc3)N4C(=O)C=CC4=O

InChI

1S/C20H16N2O5/c1-26-16-9-12-11-21(20(25)15(12)10-17(16)27-2)13-3-5-14(6-4-13)22-18(23)7-8-19(22)24/h3-10H,11H2,1-2H3

InChI key

ISCHQGBNSNVWCQ-UHFFFAOYSA-N

Application

N-[4-(5,6-Dimethoxy-N-phthalimidinyl)phenyl]maleimide (DPM) is used to fluorescence label proteins via their sulfhydryl groups. Nonfluorescent N-substituted maleimides react selectively with thiol compounds to form fluorescent derivatives. Fluorescent intensity of the dimethoxyphthalimidyl group is higher than that of the non substituted phthalimidyl group.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Pierre-Yves Musso et al.
Nature communications, 8(1), 1803-1803 (2017-11-29)
Non-caloric artificial sweeteners (NAS) are widely used in modern human food, raising the question about their health impact. Here we have asked whether NAS consumption is a neutral experience at neural and behavioral level, or if NAS can be interpreted
Eric J Esswein et al.
Journal of occupational and environmental hygiene, 15(1), 63-70 (2017-10-21)
Diesel engines serve many purposes in modern oil and gas extraction activities. Diesel particulate matter (DPM) emitted from diesel engines is a complex aerosol that may cause adverse health effects depending on exposure dose and duration. This study reports on
Mike Goblirsch et al.
PloS one, 8(3), e58165-e58165 (2013-03-14)
Persistent exposure to mite pests, poor nutrition, pesticides, and pathogens threaten honey bee survival. In healthy colonies, the interaction of the yolk precursor protein, vitellogenin (Vg), and endocrine factor, juvenile hormone (JH), functions as a pacemaker driving the sequence of
P N McCormick et al.
Neuropharmacology, 89, 225-231 (2014-10-07)
Pramipexole is a clinically important dopamine receptor agonist with reported selectivity for dopamine D3 receptors over other dopaminergic and non-dopaminergic sites. Many of its behavioural effects are therefore attributed to D3 receptor activity. Here we relate pramipexole's ex vivo D2 and
Aude Picard et al.
Frontiers in microbiology, 2, 263-263 (2011-12-31)
Microbial heterotrophic activity was investigated in oxic sub-seafloor sediments at North Pond, a sediment pond situated at 23°N on the western flank of the Mid-Atlantic Ridge. The North Pond sediments underlie the oligotrophic North Atlantic Gyre at 4580-m water depth

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