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Merck
CN

39197

N-Dansylethylenediamine

suitable for fluorescence

Synonym(s):

N-(2-Aminoethyl)-5-dimethylamino-1-naphthalenesulfonamide, N-(2-Aminoethyl)dansylamide, DNSEDA, NSC 666752

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About This Item

Empirical Formula (Hill Notation):
C14H19N3O2S
CAS Number:
35060-08-3
Molecular Weight:
293.38
UNSPSC Code:
12352202
NACRES:
NA.32
PubChem Substance ID:
329755827
MDL number:
MFCD00467523
Beilstein/REAXYS Number:
2817535

Key Documents

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Product Name

N-Dansylethylenediamine, suitable for fluorescence

InChI

1S/C14H19N3O2S/c1-17(2)13-7-3-6-12-11(13)5-4-8-14(12)20(18,19)16-10-9-15/h3-8,16H,9-10,15H2,1-2H3

InChI key

CSJXLKVNKAXFSI-UHFFFAOYSA-N

SMILES string

CN(C)c1cccc2c(cccc12)S(=O)(=O)NCCN

assay

≥90% (TLC)

solubility

methanol: 1 mg/mL, clear, slightly yellow to deep yellow

fluorescence

λex 360 nm; λem 530 nm±10 nm in methanol

suitability

suitable for fluorescence

storage temp.

−20°C

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pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCBK3056V

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Emma L Doyle et al.
Journal of the American Chemical Society, 125(15), 4593-4599 (2003-04-10)
The binding of copper(II) ions to membrane-bound synthetic receptors has been investigated. Complexation fitted a 4:1 receptor:copper(II) model, and the observed binding constants are significantly enhanced at the membrane relative to solution; these effects can be explained by the lower
E Kim et al.
Biophysical journal, 69(5), 2024-2032 (1995-11-01)
Gln-41 on G-actin was specifically labeled with a fluorescent probe, dansyl ethylenediamine (DED), via transglutaminase reaction to explore the conformational changes in subdomain 2 of actin. Replacement of Ca2+ with Mg2+ and ATP with ADP on G-actin produced large changes
E Kim et al.
Biophysical journal, 70(3), 1439-1446 (1996-03-01)
Actin labeled at Gln-41 with dansyl ethylenediamine (DED) via transglutaminase reaction was used for monitoring the interaction of myosin subfragment 1 (S1) with the His-40-Gly-42 site in the 38-52 loop on F-actin. Proteolytic digestions of F-actin with subtilisin and trypsin
Xiaolan Yang et al.
BMC biotechnology, 11, 44-44 (2011-05-07)
The combinatorial library strategy of using multiple candidate ligands in mixtures as library members is ideal in terms of cost and efficiency, but needs special screening methods to estimate the affinities of candidate ligands in such mixtures. Herein, a new
D H Atha et al.
Biochimica et biophysica acta, 785(1-2), 1-6 (1984-02-28)
Derivatives of human thrombin and antithrombin III with fluorescent labels covalently attached to their carbohydrate moieties were prepared by reaction of periodate-oxidized proteins with amino derivatives of dansyl, fluorescein and pyrene. The labeled derivatives retained full biological activity, including their
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