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Merck
CN

39490

Sigma-Aldrich

MEGA-8 500 mM solution

Synonym(s):

MEGA-8 solution, Detergent Screening Solution 35/Kit-No 66317

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About This Item

CAS Number:
85316-98-9
MDL number:
MFCD00134152
UNSPSC Code:
12352200
PubChem Substance ID:
57649901

Key Documents

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description

non-ionic

CMC

58

application(s)

sample preservation

storage temp.

2-8°C

SMILES string

CCCCCCCC(=O)N(C)C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

InChI

1S/C15H31NO6/c1-3-4-5-6-7-8-13(20)16(2)9-11(18)14(21)15(22)12(19)10-17/h11-12,14-15,17-19,21-22H,3-10H2,1-2H3/t11-,12+,14+,15+/m0/s1

InChI key

SBWGZAXBCCNRTM-CTHBEMJXSA-N

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCBM3001V
BCBM0903V
BCBJ5595V
1068551

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G A Jeffrey et al.
Acta crystallographica. Section B, Structural science, 45 ( Pt 4), 447-452 (1989-08-01)
1-Deoxy-(N-methyloctanamido)-D-glucitol, C15H31NO6 (MEGA-8), crystallizes in space group P2(1)2(1)2(1), Mr = 321.4, a = 4.865 (1), b = 9.186 (3), c = 39.097 (9) A, V = 1747.24 A3, Z = 4, Dx = 1.22 Mg m-3, lambda (Cu K alpha)
P Banerjee et al.
Chemistry and physics of lipids, 77(1), 65-78 (1995-08-01)
Membrane proteins are typically extracted by detergent concentrations of 0.5-2.0%, using detergent/protein ratios of 1:1 to 3:1. We have compared the ability of 14 different detergents from seven different structural and ionic classes, at a concentration of 2.0% and a
Bo Y Baker et al.
Biochemistry, 50(44), 9520-9531 (2011-10-08)
Membrane-bound phosphodiesterase 6 (PDE6) plays an important role in visual signal transduction by regulating cGMP levels in rod photoreceptor cells. Our understanding of PDE6 catalysis and structure suffers from inadequate characterization of the α and β subunit catalytic core, interactions
A Walter et al.
Biochimica et biophysica acta, 1029(1), 67-74 (1990-11-02)
The critical micelle concentration (CMC) and the ability to solubilize and form vesicles from phospholipids are important criteria for the selection of a surfactant for reconstitution protocols. The CMC and its temperature dependence were determined for an homologous series of
Jeong-Soo Ko et al.
Colloids and surfaces. B, Biointerfaces, 45(2), 90-103 (2005-09-07)
By means of surface tension measurement (Wilhelmy method), micellization and adsorbed film formation were investigated for three combinations of mixed surfactant systems, all of which are used for solubilizing membrane proteins: a typical zwitterionic surfactant, CHAPS (a derivative of cholic
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