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Merck
CN

42627

1,2-Dipalmitoyl-sn-glycero-3-phospho-rac-(1-glycerol) ammonium salt

≥96.0% (TLC)

Synonym(s):

1,2-Dihexadecanoyl-sn-glycero-3-phospho-(1′-rac-glycerol) ammonium salt, 1,2-Dipalmitoyl-sn-glycero-3-phosphoglycerol, DPPG-NH4, L-α-Phosphatidyl-DL-glycerol, dipalmitoyl ammonium salt, PG(16:0/16:0)

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About This Item

Linear Formula:
C38H75O10P · NH3
CAS Number:
1373168-73-0
Molecular Weight:
740.00
UNSPSC Code:
12352211
PubChem Substance ID:
329756250
NACRES:
NA.85

Key Documents

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InChI

1S/C38H75O10P.H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-37(41)45-33-36(34-47-49(43,44)46-32-35(40)31-39)48-38(42)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h35-36,39-40H,3-34H2,1-2H3,(H,43,44);1H3/t35?,36-;/m1./s1

InChI key

KSVUSCAQEBSOIJ-ODZMYOIVSA-N

biological source

synthetic

assay

≥96.0% (TLC)

form

powder

functional group

phospholipid

lipid type

phosphoglycerides

storage temp.

−20°C

Biochem/physiol Actions

One of several phospholipids that serves as surfactant on lung alveolar membranes. Incorporated in small unilamellar vesicles, DPPG specifically (not other phospholipids tested) provides protection against infection by vaccinia virus.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCCD7029
BCCD1770
BCBL4717V
1432671V
1432671

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Julien Perino et al.
Antiviral research, 89(1), 89-97 (2010-11-26)
Vaccinia virus (VACV) was used as a surrogate of Variola virus (genus Orthopoxvirus), the causative agent of smallpox, to study orthopoxvirus infection via the respiratory airway. Lung surfactant, a physiological barrier to infection encountered by the virus, is predominantly composed

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