44977
DISBAC2(3), Voltage Sensitive Probe
≥98% (HPLC)
Synonym(s):
5-[3-(1,3-Diethylhexahydro-4,6-dioxo-2-thioxo-5-pyrimidinyl)-2-propen-1-ylidene]-1,3-diethyldihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione, Bis(1,3-diethylthiobarbituric acid)trimethine oxonol
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About This Item
Empirical Formula (Hill Notation):
C19H24N4O4S2
CAS Number:
Molecular Weight:
436.55
UNSPSC Code:
12352108
NACRES:
NA.32
PubChem Substance ID:
EC Number:
256-325-5
Beilstein/REAXYS Number:
1232950
MDL number:
Quality Segment
assay
≥98% (HPLC)
fluorescence
λex 535 nm; λem 560 nm in DMSO
suitability
complies for Infrared spectrum
storage temp.
−20°C
SMILES string
CCN1C(=O)C(\C=C\C=C2\C(=O)N(CC)C(=S)N(CC)C2=O)C(=O)N(CC)C1=S
InChI
1S/C19H24N4O4S2/c1-5-20-14(24)12(15(25)21(6-2)18(20)28)10-9-11-13-16(26)22(7-3)19(29)23(8-4)17(13)27/h9-12H,5-8H2,1-4H3/b10-9+
InChI key
VJYNRXFXHKIGLT-MDZDMXLPSA-N
Application
DISBAC2(3), Voltage Sensitive Probe is used for single-cell fluorescence imaging of transmembrane conductance and potential change.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Alexander S Tatikolov et al.
Biophysical chemistry, 107(1), 33-49 (2004-02-12)
Non-covalent interactions between polymethine dyes of various types (cationic and anionic thiacarbocyanines as well as anionic oxonols and tetracyanopolymethines) and human serum albumin (HSA) were studied by means of absorption, fluorescence and circular dichroism (CD) spectroscopies. Complexation with the protein
N Minami et al.
Journal of neural transmission. General section, 97(1), 65-72 (1994-01-01)
Effects of cyclic AMP on membrane potentials were examined by measuring the changes of bis-oxonol fluorescence in bovine adrenal medullary chromaffin cells. 8-Bromo cyclic AMP (8Br-cAMP) or forskolin caused a gradual and long lasting increase of the fluorescence intensity. The
In situ study of the membrane potential in microvascular endothelial cells using a fluorescent probe.
K Miao et al.
Microvascular research, 48(1), 135-142 (1994-07-01)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 44977-1MG | 04061823367226 |