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Merck
CN

45165

EMPIGEN® BB detergent

~35% active substance in H2O

Synonym(s):

N,N-Dimethyl-N-dodecylglycine betaine, N-(Alkyl C10-C16)-N,N-dimethylglycine betaine

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About This Item

Linear Formula:
CH3(CH2)8-14CH2N+(CH3)2CH2COO-
CAS Number:
66455-29-6
EC Number:
266-368-1
UNSPSC Code:
12161900
PubChem Substance ID:
57650261
Beilstein/REAXYS Number:
3670807
MDL number:
MFCD00084742

Key Documents

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description

zwitterionic

mol wt

Mr ~279

concentration

~35% active substance in H2O

CMC

1.6-2.1 mM (20-25°C)

density

1.04 g/mL at 20 °C

λ

neat

UV absorption

λ: 417 nm Amax: 0.055, λ: 441 nm Amax: 0.037

SMILES string

CCCCCCCCCCCC[N+](C)(C)CC([O-])=O

InChI

1S/C16H33NO2/c1-4-5-6-7-8-9-10-11-12-13-14-17(2,3)15-16(18)19/h4-15H2,1-3H3

InChI key

DVEKCXOJTLDBFE-UHFFFAOYSA-N

Application

Zwitterionic detergent (an amine betaine), useful for solubilization of membrane proteins. Used for preparing viral antigens by removing kinases.

Legal Information

EMPIGEN is a registered trademark of Huntsman Corporation

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

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Certificates of Analysis (COA)

Lot/Batch Number
BCBC8449V
BCBC8449
1384611
1341642
376664/1

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Thorson, J.A., et al.
Microbiology, 18, 5229-5229 (1998)
Ryosuke Nagashima et al.
The Journal of cell biology, 218(5), 1511-1530 (2019-03-03)
Although chromatin organization and dynamics play a critical role in gene transcription, how they interplay remains unclear. To approach this issue, we investigated genome-wide chromatin behavior under various transcriptional conditions in living human cells using single-nucleosome imaging. While transcription by

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Detergents Properties and Applications

A guide displaying detergents' specifications and applications. The detergents are seperated into four groups (nonionic, anionic, cationic, zwitterionic) based on their hydrophillic head group. The guide also contains Non-Detergent Sulfobetaines.

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