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Merck
CN

45690

Erythrosin extra bluish

suitable for microscopy

Synonym(s):

2′,4′,5′,7′-Tetraiodofluorescein disodium salt, Acid Red 51, Iodoeosin

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About This Item

Empirical Formula (Hill Notation):
C20H6I4Na2O5
CAS Number:
16423-68-0
Molecular Weight:
879.86
Colour Index Number:
45430
Beilstein:
1443945
EC Number:
240-474-8
MDL number:
MFCD00144257
UNSPSC Code:
12171500
PubChem Substance ID:
329756903
NACRES:
NA.47

Key Documents

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form

solid

Quality Level

100

technique(s)

titration: suitable

suitability

suitable for microscopy

SMILES string

[Na+].[Na+].[O-]c1c(I)cc2c(Oc3c(I)c([O-])c(I)cc3C24OC(=O)c5ccccc45)c1I

InChI

1S/C20H8I4O5.2Na/c21-11-5-9-17(13(23)15(11)25)28-18-10(6-12(22)16(26)14(18)24)20(9)8-4-2-1-3-7(8)19(27)29-20;;/h1-6,25-26H;;/q;2*+1/p-2

InChI key

RAGZEDHHTPQLAI-UHFFFAOYSA-L

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General description

Erythrosin extra bluish is a brown color powder, that is soluble in ethanol and water. Its pH ranges from 2.5 to 4. It is used in color filters, light emitting diodes, cosmetics, hair dyes etc. It has several biological applications like detecting gene expression, treating age related macular degeneration, diabetes, obesity etc.

Pictograms

Exclamation markEnvironment
GHS07,GHS09

Signal Word

Warning

Hazard Statements

H302 - H411

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

359.6 °F - closed cup

Flash Point(C)

182 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL3812
BCCH5535
BCCJ0693
BCCG2000
BCCD1099

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Anna Carolina Borges Pereira Costa et al.
Archives of oral biology, 56(11), 1299-1305 (2011-06-28)
The effect of erythrosine- and LED-mediated photodynamic therapy (PDT) on planktonic cultures and biofilms of Candida albicans and Candida dubliniensis was evaluated. Planktonic cultures of standardized suspensions (10(6)cells/mL) of C. albicans and C. dubliniensis were treated with erythrosine concentrations of
Ying-Ju Huang et al.
ChemMedChem, 7(4), 571-577 (2012-02-23)
SecA is a central component of the general secretion system that is essential for bacterial growth and thus an ideal target for antimicrobial agents. A series of fluorescein analogues were first screened against the ATPase activity using the truncated unregulated
Juliana P M L Rolim et al.
Journal of photochemistry and photobiology. B, Biology, 106, 40-46 (2011-11-11)
Several photosensitizers have been used against oral bacteria without standardization. Singlet oxygen ((1)O(2)) is an aggressive chemical species that can kill cells through apoptosis or necrosis. to compare the antimicrobial activity of photodynamic therapy (PDT) with different photosensitizers at the
Kamilla Swiech et al.
BMC biotechnology, 11, 114-114 (2011-11-26)
Hemophilia A is a bleeding disorder caused by deficiency in coagulation factor VIII. Recombinant factor VIII (rFVIII) is an alternative to plasma-derived FVIII for the treatment of hemophilia A. However, commercial manufacturing of rFVIII products is inefficient and costly and
Chueh-Pin Chen et al.
Photochemistry and photobiology, 88(3), 570-576 (2012-01-31)
The growing resistance to antibiotics has rendered antimicrobial photodynamic inactivation (PDI) an attractive alternative treatment modality for infectious diseases. Chitosan (CS) was shown to further potentiate the PDI effect of photosensitizers and was therefore used in this study to investigate
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