46041
Esterase basic kit
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About This Item
CAS Number:
UNSPSC Code:
12352204
PubChem Substance ID:
EC Number:
232-773-7
MDL number:
storage temp.
−20°C
SMILES string
C[C@]12CC[C@@H](O)C[C@@H]1CC[C@@H]3[C@@H]2CC[C@@]4(C)[C@H]3CCC4=O
InChI
1S/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12-16,20H,3-11H2,1-2H3/t12-,13+,14-,15-,16-,18-,19-/m0/s1
InChI key
QGXBDMJGAMFCBF-HLUDHZFRSA-N
Other Notes
Composition:
96667 Esterase from Bacillus subtilis, 10 mg
51963 Esterase from Bacillus subtilis, 10 mg
46051 Esterase from Bacillus stearothermophilus, 10 mg
79208 Esterase from Rhizopus oryzae, 100 mg
46056 Esterase from Candida lipolytica, 50 mg
46059 Esterase from Mucor miehei, 50 mg
46069 Esterase from horse liver, 50 mg
46071 Esterase from Saccharomyces cerevisiae, 25 mg
46058 Esterase from hog liver, 10 mg
75742 Esterase Pseudomonas fluorescens, recombinant from E. coli, 10 mg
96667 Esterase from Bacillus subtilis, 10 mg
51963 Esterase from Bacillus subtilis, 10 mg
46051 Esterase from Bacillus stearothermophilus, 10 mg
79208 Esterase from Rhizopus oryzae, 100 mg
46056 Esterase from Candida lipolytica, 50 mg
46059 Esterase from Mucor miehei, 50 mg
46069 Esterase from horse liver, 50 mg
46071 Esterase from Saccharomyces cerevisiae, 25 mg
46058 Esterase from hog liver, 10 mg
75742 Esterase Pseudomonas fluorescens, recombinant from E. coli, 10 mg
signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
Storage Class
10 - Combustible liquids
wgk
WGK 1
Regulatory Information
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Jamie B Scaglione et al.
Journal of medicinal chemistry, 51(5), 1309-1318 (2008-02-16)
Although the structural features of binding sites for neuroactive steroids on gamma-aminobutryic acid type A (GABA A) receptors are still largely unknown, structure-activity studies have established a pharmacophore for potent enhancement of GABA A receptor function by neuroactive steroids. This
Bryson W Katona et al.
European journal of medicinal chemistry, 43(1), 107-113 (2007-04-17)
Allopregnanolone (1) and pregnanolone (2), steroids containing a 17beta-acetyl group, are potent enhancers of GABA (gamma-aminobutyric acid) action at GABAA receptors. Their effects are enantioselective with the non-naturally occurring enantiomers (ent-1 and ent-2) being less potent. Androsterone (3) and etiocholanolone
Jamie B Scaglione et al.
Journal of medicinal chemistry, 49(15), 4595-4605 (2006-07-21)
Benz[f]indenes are tricyclic compounds with a linear 6-6-5 fused carbocyclic ring system. When properly substituted, benz[f]indenes can satisfy the pharmacophore requirements of the critical hydrogen-bond donor and acceptor groups found in neuroactive steroids that modulate gamma-aminobutyric acidA (GABAA) receptor function.
Hiroyuki Sato et al.
Journal of medicinal chemistry, 51(6), 1831-1841 (2008-03-01)
TGR5, a metabotropic receptor that is G-protein-coupled to the induction of adenylate cyclase, has been recognized as the molecular link connecting bile acids to the control of energy and glucose homeostasis. With the aim of disclosing novel selective modulators of
Edith Bellavance et al.
Journal of medicinal chemistry, 52(23), 7488-7502 (2009-09-24)
17beta-Hydroxysteroid dehydrogenase type 7 (17beta-HSD7) catalyzes the reduction of estrone (E(1)) into estradiol (E(2)) and of dihydrotestosterone (DHT) into 5alpha-androstane-3beta,17beta-diol (3beta-diol), therefore modulating the level of mitogenic estrogens and androgens in humans. By classical and parallel chemistry, we generated several
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