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Merck
CN

46117

4,4′-Oxydianiline

analytical standard

Synonym(s):

4,4′-Diaminodiphenyl ether, 4-Aminophenyl ether

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About This Item

Linear Formula:
O(C6H4NH2)2
CAS Number:
Molecular Weight:
200.24
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
202-977-0
Beilstein/REAXYS Number:
475735
MDL number:
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InChI key

HLBLWEWZXPIGSM-UHFFFAOYSA-N

InChI

1S/C12H12N2O/c13-9-1-5-11(6-2-9)15-12-7-3-10(14)4-8-12/h1-8H,13-14H2

SMILES string

Nc1ccc(Oc2ccc(N)cc2)cc1

grade

analytical standard

vapor pressure

10 mmHg ( 240 °C)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

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General description

4,4′-Oxydianiline is a potent carcinogen belonging to the class of aromatic amines. It is commonly used in the production of pesticides, pharmaceuticals, dyes, packaging of food products, etc.
This compound is listed in the SVHC (Substances of very high concern) candidate list of ECHA (European Chemicals Agency)

Application

4,4′-Oxydianiline may be used as an analytical reference standard for the quantification of the analyte in water samples and water food simulant using different chromatography techniques.

Disclaimer

Restricted to professional users. Attention − Avoid exposure − obtain special instructions before use.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 1 - Carc. 1B - Muta. 1B - Repr. 2 - Skin Sens. 1 - STOT RE 2 Oral

target_organs

Thyroid

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

426.2 °F - closed cup

flash_point_c

219 °C - closed cup


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Analysis of carcinogenic aromatic amines in water samples by solid-phase microextraction coupled with high-performance liquid chromatography
Chang Y-W, et al.
Analytica Chimica Acta, 495(1-2), 109-122 (2003)
Determination of primary aromatic amines in water food simulant using solid-phase analytical derivatization followed by gas chromatography coupled with mass spectrometry
Brede C, et al.
Journal of Chromatography A, 983(1-2), 35-42 (2003)
[Cardiotoxic action of 4,4-diaminodiphenyl ether].
V A Kondratiuk et al.
Gigiena i sanitariia, (6)(6), 31-34 (1986-06-01)
[Functional and morphologic changes in the myocardium caused by chemical damage].
M S Gnatiuk et al.
Gigiena i sanitariia, (2)(2), 54-57 (1990-02-01)
4,4'-Oxydianiline.
Report on carcinogens : carcinogen profiles, 10, 190-191 (2004-08-27)

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