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Merck
CN

46133

Supelco

Chlortetracycline hydrochloride

VETRANAL®, analytical standard

Synonym(s):

7-Chlorotetracycline hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C22H23ClN2O8 · HCl
CAS Number:
Molecular Weight:
515.34
Beilstein:
3858364
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
E Number:
E702
NACRES:
NA.24
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grade

analytical standard

Agency

EPA 1694

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

210-215 °C (dec.) (lit.)

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria

application(s)

cleaning products
clinical
cosmetics
environmental
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)

format

neat

Mode of action

protein synthesis | interferes

storage temp.

2-8°C

SMILES string

Cl.CN(C)[C@H]1[C@@H]2CC3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c4c(O)ccc(Cl)c4[C@@]3(C)O

InChI

1S/C22H23ClN2O8.ClH/c1-21(32)7-6-8-15(25(2)3)17(28)13(20(24)31)19(30)22(8,33)18(29)11(7)16(27)12-10(26)5-4-9(23)14(12)21;/h4-5,7-8,15,26,28-29,32-33H,6H2,1-3H3,(H2,24,31);1H/t7?,8-,15-,21-,22-;/m0./s1

InChI key

CBHYYLPALVVVEY-LYNLVHCPSA-N

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General description

Chemical structure: tetracycline

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Health hazardExclamation mark

Signal Word

Warning

Hazard Classifications

Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

涉药品监管产品
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Hui Fu et al.
Wei sheng yan jiu = Journal of hygiene research, 41(2), 282-286 (2012-05-23)
To develop a method for determination of the Metronidazole, Chlortetracycline hydrochloride, Oxytetracycline dihydrate, Minocycline hydrochloride, Erythromycin and Tetracycline hydrochloride in disinfection products by high performance liquid chromatography tandem mass spectrometry(LC-MS/MS). Samples were extracted by methanol and filtered through 0.45 microm
Erin L Strait et al.
Journal of the American Veterinary Medical Association, 241(12), 1666-1667 (2012-12-12)
A sudden onset of extreme dysgalactia in gilts and sows in a 1,000-head farrow-to-wean herd was observed in December 2009. Signs of dysgalactia were identified in sows beginning 1 day after parturition and lasted 4 to 6 days. This resulted
T L Poole et al.
Journal of applied microbiology, 113(3), 659-668 (2012-06-22)
To determine the differences in competitive fitness among Escherichia coli strains with different plasmid profiles when grown in suspension with commensal faecal bacteria from growing swine fed chlortetracycline-supplemented or unsupplemented diets. Five multiple drug-resistant (MDR) E. coli strains that possessed
VMD revises advice on chlortetracyline use in calf milk replacer.
The Veterinary record, 172(3), 58-58 (2013-01-22)
M Hammad Khan et al.
Environmental technology, 34(1-4), 495-502 (2013-03-28)
Chlortetracycline (CTC) is a hazardous material in aquatic environments. This study was focused on optimization of photocatalytic ozonation processes for removal of CTC from wastewater at pH 2.2 and 7.0. In this study, the tested processes for CTC removal were

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