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Merck
CN

46133

Chlortetracycline hydrochloride

VETRANAL®, analytical standard

Synonym(s):

7-Chlorotetracycline hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C22H23ClN2O8 · HCl
CAS Number:
64-72-2
Molecular Weight:
515.34
NACRES:
NA.24
E Number:
E702
PubChem Substance ID:
329757081
UNSPSC Code:
41116107
EC Number:
200-591-7
MDL number:
MFCD00082440
Beilstein/REAXYS Number:
3858364

Key Documents

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Product Name

Chlortetracycline hydrochloride, VETRANAL®, analytical standard

InChI key

CBHYYLPALVVVEY-LYNLVHCPSA-N

InChI

1S/C22H23ClN2O8.ClH/c1-21(32)7-6-8-15(25(2)3)17(28)13(20(24)31)19(30)22(8,33)18(29)11(7)16(27)12-10(26)5-4-9(23)14(12)21;/h4-5,7-8,15,26,28-29,32-33H,6H2,1-3H3,(H2,24,31);1H/t7?,8-,15-,21-,22-;/m0./s1

SMILES string

Cl.CN(C)[C@H]1[C@@H]2CC3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c4c(O)ccc(Cl)c4[C@@]3(C)O

grade

analytical standard

agency

EPA 1694

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

210-215 °C (dec.) (lit.)

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria

application(s)

cleaning products
clinical
cosmetics
environmental
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)

format

neat

mode of action

protein synthesis | interferes

storage temp.

2-8°C

Quality Level

200

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Related Categories

General description

Chemical structure: tetracycline

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

涉药品监管产品
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Certificates of Analysis (COA)

Lot/Batch Number
BCCH2550
BCCG5799
BCBT9837
BCBR8687V

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Hui Fu et al.
Wei sheng yan jiu = Journal of hygiene research, 41(2), 282-286 (2012-05-23)
To develop a method for determination of the Metronidazole, Chlortetracycline hydrochloride, Oxytetracycline dihydrate, Minocycline hydrochloride, Erythromycin and Tetracycline hydrochloride in disinfection products by high performance liquid chromatography tandem mass spectrometry(LC-MS/MS). Samples were extracted by methanol and filtered through 0.45 microm
Menghong Dai et al.
Journal of microbiology (Seoul, Korea), 50(5), 807-812 (2012-11-06)
The present criteria and rules controlling the approval of the use of probiotics are limited to antibiotic resistance patterns and the presence of antibiotic resistance genes in bacteria. There is little information available in the literature regarding the risk of
Luxi Dong et al.
Chemosphere, 89(1), 44-51 (2012-06-01)
DNA damage and changes in enzyme activities were used as biomarkers to evaluate the genotoxicity and oxidative stress of tetracycline and chlortetracycline on the earthworm Eisenia fetida. The results showed that both antibiotics induced significant genotoxicity on earthworms in a
C L Levesque et al.
Journal of animal science, 90 Suppl 4, 448-450 (2013-02-13)
A longitudinal study was conducted in pigs to evaluate the effect of nutrition and use of antibiotics for weaner pigs on ileal bacterial microbiota. Forty-eight pigs were weaned at 21 ± 2 d of age and fed a high complexity
Erin L Strait et al.
Journal of the American Veterinary Medical Association, 241(12), 1666-1667 (2012-12-12)
A sudden onset of extreme dysgalactia in gilts and sows in a 1,000-head farrow-to-wean herd was observed in December 2009. Signs of dysgalactia were identified in sows beginning 1 day after parturition and lasted 4 to 6 days. This resulted
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