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Merck
CN

46970

Fluorescein sodium salt

p.a.

Synonym(s):

Acid Yellow 73, D&C;Yellow No. 8, NaFl, NaFluo, Sodium fluorescein, Uranine

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About This Item

Empirical Formula (Hill Notation):
C20H10Na2O5
CAS Number:
518-47-8
Molecular Weight:
376.27
Colour Index Number:
45350
Beilstein:
3833041
EC Number:
208-253-0
MDL number:
MFCD00167039
UNSPSC Code:
12171501
PubChem Substance ID:
329757279
NACRES:
NA.32

Key Documents

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grade

p.a.

Quality Level

100

form

powder

fluorescence

λex 460 nm; λem 515 nm(lit.)

SMILES string

[Na+].[Na+].[O-]c1ccc2c(Oc3cc([O-])ccc3C24OC(=O)c5ccccc45)c1

InChI

1S/C20H12O5.2Na/c21-11-5-7-15-17(9-11)24-18-10-12(22)6-8-16(18)20(15)14-4-2-1-3-13(14)19(23)25-20;;/h1-10,21-22H;;/q;2*+1/p-2

InChI key

RGPLGPBQJOQFJS-UHFFFAOYSA-L

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General description

Fluorescein Sodium Salt (FSS) is a xanthene dye having a polycrystalline structure with a monoclinic system. Fluorescein is a synthetic organic compound available as a dark orange/red powder soluble in water and alcohol.

Application

Fluorescein Sodium Salt (FSS) is used to conduct in-vivo skin studies.

Xanthene fluorophores, like Fluorescein Sodium Salt (FSS), are versatile compounds used across diverse fields of chemistry and life sciences.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

423.7 °F - Pensky-Martens closed cup

Flash Point(C)

217.6 °C - Pensky-Martens closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN5565
BCCL3966
BCCK5378
BCCH4984
BCCG3521

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Joshua L Turnbull et al.
Journal of the American Chemical Society, 143(16), 6194-6201 (2021-04-03)
Xanthene fluorophores, like fluorescein, have been versatile molecules across diverse fields of chemistry and life sciences. Despite the ubiquity of 3-carboxy and 3-sulfonofluorescein for the last 150 years, to date, no reports of 3-phosphonofluorescein exist. Here, we report the synthesis
Jacob Beal et al.
Communications biology, 3(1), 512-512 (2020-09-19)
Optical density (OD) is widely used to estimate the density of cells in liquid culture, but cannot be compared between instruments without a standardized calibration protocol and is challenging to relate to actual cell count. We address this with an
Beau J Fenner et al.
Investigative ophthalmology & visual science, 54(13), 8013-8019 (2013-11-14)
To determine the reliability of single- and double-zone corneal fluorescent staining compared with five-zone analysis for the prediction of dry eye disease. Prospective study of 510 subjects with dry eye disease characterized using corneal fluorescein staining, Schirmer scores, and tear
Tomoaki Murakami et al.
Ophthalmology, 120(12), 2596-2603 (2013-08-21)
To study the association between the fluorescence levels on fluorescein angiography images and the characteristics on spectral-domain optical coherence tomography (SD OCT) images in diabetic macular edema (DME). Retrospective, observational, cross-sectional study. One hundred sixty-seven consecutive eyes of 116 patients
Wee Yang Ng et al.
Biomicrofluidics, 3(2), 22405-22405 (2009-08-21)
This paper investigates the phenomenon of Faradaic charging in ac electrokinetics. Faradaic reactions were suggested as a key effect responsible for the reversal of pumping direction in ac micropumps. However, this hypothesis has yet to be proven convincingly and directly.
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