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Merck
CN

49622

L-Glutamic acid 1-(4-nitroanilide)

≥98.0% (T)

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About This Item

Empirical Formula (Hill Notation):
C11H13N3O5
CAS Number:
Molecular Weight:
267.24
Beilstein:
3036815
EC Number:
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
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Assay

≥98.0% (T)

form

powder

optical activity

[α]20/D +81.0±3.0°, c = 1% in 5 M HCl

storage temp.

2-8°C

SMILES string

CC(C)(C)OC(=O)N[C@@H](CCC(O)=O)C(=O)Oc1ccc(cc1)[N+]([O-])=O

InChI

1S/C16H20N2O8/c1-16(2,3)26-15(22)17-12(8-9-13(19)20)14(21)25-11-6-4-10(5-7-11)18(23)24/h4-7,12H,8-9H2,1-3H3,(H,17,22)(H,19,20)/t12-/m0/s1

InChI key

TXKOUVRCDMSOJZ-LBPRGKRZSA-N

Other Notes

Chromogenic substrate for the assay (determination of liberated 4-nitroaniline at 410 nm) of aminopeptidase A (EC 3.4.11.7)

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Kristin Williams et al.
Biochemistry, 48(11), 2459-2467 (2009-03-05)
Helicobacter pylori gamma-glutamyltranspeptidase (HpGT) is a general gamma-glutamyl hydrolase and a demonstrated virulence factor. The enzyme confers a growth advantage to the bacterium, providing essential amino acid precursors by initiating the degradation of extracellular glutathione and glutamine. HpGT is a
A Benajiba et al.
European journal of biochemistry, 107(2), 381-388 (1980-06-01)
The aminopeptidase A of the porcine intestinal brush-border membrane has been purified following solubilization by trypsin (p-form) or Emulphogen (d-form). Full purification of d-amino-peptidase A required the use of anti-impurities immunoabsorbant chromatography. The d-amino-peptidase A constitutes about 4% of the
Terence S Crofts et al.
Nature chemical biology, 14(6), 556-564 (2018-05-02)
The soil microbiome can produce, resist, or degrade antibiotics and even catabolize them. While resistance genes are widely distributed in the soil, there is a dearth of knowledge concerning antibiotic catabolism. Here we describe a pathway for penicillin catabolism in

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