49622
L-Glutamic acid 1-(4-nitroanilide)
≥98.0% (T)
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About This Item
Empirical Formula (Hill Notation):
C11H13N3O5
CAS Number:
Molecular Weight:
267.24
EC Number:
245-994-9
UNSPSC Code:
12352204
PubChem Substance ID:
Beilstein/REAXYS Number:
3036815
MDL number:
InChI key
TXKOUVRCDMSOJZ-LBPRGKRZSA-N
InChI
1S/C16H20N2O8/c1-16(2,3)26-15(22)17-12(8-9-13(19)20)14(21)25-11-6-4-10(5-7-11)18(23)24/h4-7,12H,8-9H2,1-3H3,(H,17,22)(H,19,20)/t12-/m0/s1
SMILES string
CC(C)(C)OC(=O)N[C@@H](CCC(O)=O)C(=O)Oc1ccc(cc1)[N+]([O-])=O
assay
≥98.0% (T)
form
powder
optical activity
[α]20/D +81.0±3.0°, c = 1% in 5 M HCl
storage temp.
2-8°C
Other Notes
Chromogenic substrate for the assay (determination of liberated 4-nitroaniline at 410 nm) of aminopeptidase A (EC 3.4.11.7)
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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A Benajiba et al.
European journal of biochemistry, 107(2), 381-388 (1980-06-01)
The aminopeptidase A of the porcine intestinal brush-border membrane has been purified following solubilization by trypsin (p-form) or Emulphogen (d-form). Full purification of d-amino-peptidase A required the use of anti-impurities immunoabsorbant chromatography. The d-amino-peptidase A constitutes about 4% of the
Kristin Williams et al.
Biochemistry, 48(11), 2459-2467 (2009-03-05)
Helicobacter pylori gamma-glutamyltranspeptidase (HpGT) is a general gamma-glutamyl hydrolase and a demonstrated virulence factor. The enzyme confers a growth advantage to the bacterium, providing essential amino acid precursors by initiating the degradation of extracellular glutathione and glutamine. HpGT is a
Terence S Crofts et al.
Nature chemical biology, 14(6), 556-564 (2018-05-02)
The soil microbiome can produce, resist, or degrade antibiotics and even catabolize them. While resistance genes are widely distributed in the soil, there is a dearth of knowledge concerning antibiotic catabolism. Here we describe a pathway for penicillin catabolism in
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