49753
Glutathione Peroxidase from bovine erythrocytes
lyophilized, powder, white, ~100 U/mg
Synonym(s):
GSH-Px, Glutathione:hydrogen-peroxide oxido-reductase
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
CAS Number:
UNSPSC Code:
12352204
EC Number:
232-749-6
MDL number:
form
powder
quality
lyophilized
specific activity
~100 U/mg
mol wt
Mr ~80000
color
white
shipped in
dry ice
storage temp.
−20°C
Biochem/physiol Actions
Protects cells against oxidative damage by catalyzing the reduction of hydrogen peroxide in the presence of reducing agent glutathione. In cellular membranes it may induce lipid peroxidation through the reduction of hydrogen peroxide or polyunsaturated fatty acid hydroperoxides.
Protects cells against oxidative damage by catalyzing the reduction of hydrogen peroxide in the presence of reducing agent glutathione. In cellular membranes it may induce lipid peroxidation through the reduction of hydrogen peroxide or polyunsaturated fatty acid hydroperoxides.
Other Notes
1 U corresponds to the amount of enzyme which catalyzes the oxidation by H2O2 of 1 μmol reduced glutathione to oxidized glutathione per minute at pH 7.0 and 25°C
Note: At the reported pH optimum of 8.8, we have found the activity to be approx. 10 times that at pH 7.0. However, to remain consistent with literature and avoid complications arising from non-enzymatic oxidation of GSH, our unit is defined at pH 7.0.
signalword
Danger
hcodes
Hazard Classifications
Resp. Sens. 1
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Rao Muralikrishna Adibhatla et al.
Free radical biology & medicine, 40(3), 376-387 (2006-01-31)
Ischemic stroke is caused by obstruction of blood flow to the brain, resulting in energy failure that initiates a complex series of metabolic events, ultimately causing neuronal death. One such critical metabolic event is the activation of phospholipase A2 (PLA2)
Glutathione peroxidase.
B Mannervik
Methods in enzymology, 113, 490-495 (1985-01-01)
F Ursini et al.
Chemistry and physics of lipids, 44(2-4), 255-276 (1987-07-01)
The present review deals with the chemical properties of selenium in relation to its antioxidant properties and its reactivity in biological systems. The interaction of selenite with thiols and glutathione and the reactivity of selenocompounds with hydroperoxides are described. After
Glutathione.
A Meister et al.
Annual review of biochemistry, 52, 711-760 (1983-01-01)
Walter A Baseler et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 304(7), R553-R565 (2013-02-15)
Mitochondrial dysfunction is a contributor to diabetic cardiomyopathy. Previously, we observed proteomic decrements within the inner mitochondrial membrane (IMM) and matrix of diabetic cardiac interfibrillar mitochondria (IFM) correlating with dysfunctional mitochondrial protein import. The goal of this study was to
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service