53340
L-Histidine dihydrochloride
≥99.0% (AT)
Synonym(s):
L-Histidine hydrochloride (1:2)
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About This Item
Empirical Formula (Hill Notation):
C6H9N3O2 · 2HCl
CAS Number:
Molecular Weight:
228.08
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
227-890-5
MDL number:
Beilstein/REAXYS Number:
6119230
Product Name
L-Histidine dihydrochloride, ≥99.0% (AT)
Quality Segment
assay
≥99.0% (AT)
form
powder or crystals
optical activity
[α]20/D +6.5±1°, c = 8% in H2O
ign. residue
≤0.1% (as SO4)
color
white
mp
240-245 °C (dec.)
solubility
H2O: soluble, saline: soluble
anion traces
sulfate (SO42-): ≤50 mg/kg
cation traces
As: ≤0.1 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, NH4+: ≤500 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg
SMILES string
Cl.Cl.N[C@@H](Cc1c[nH]cn1)C(O)=O
InChI
1S/C6H9N3O2.2ClH/c7-5(6(10)11)1-4-2-8-3-9-4;;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);2*1H/t5-;;/m0../s1
InChI key
XEJCDBUNISUVGZ-XRIGFGBMSA-N
Biochem/physiol Actions
L-Histidine is a natural proteinogenic α amino acid useful as a cell growth supplement that support protein and peptide biosynthesis. L-Histidine is studied in a wide range of applications that involve imidazole chemistry and biochemisty.
L-Histidine is a positively charged imidazole-side chain containing α amino acid. It is metabolized to histamine and is a precursor of the dipeptide carnosine. As one of the 22 proteinogenic amino acids L-His is incorporated into proteins by translation processes in vitro. L-Histidine is an essential amino acid added to cell culture media.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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