56297
Pinosylvin
≥97.0% (HPLC)
Synonym(s):
(E)-3,5-Stilbenediol, (E)-5-(2-Phenylethenyl)-1,3-benzenediol, 5-Styrylresorcinol, trans-3,5-Dihydroxystilbene, Pinosylvine
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About This Item
Empirical Formula (Hill Notation):
C14H12O2
CAS Number:
Molecular Weight:
212.24
UNSPSC Code:
41116107
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1870942
Quality Level
assay
≥97.0% (HPLC)
form
solid
storage condition
protect from light
mp
153-157 °C
shipped in
wet ice
storage temp.
2-8°C
SMILES string
Oc1cc(O)cc(\C=C\c2ccccc2)c1
InChI
1S/C14H12O2/c15-13-8-12(9-14(16)10-13)7-6-11-4-2-1-3-5-11/h1-10,15-16H/b7-6+
InChI key
YCVPRTHEGLPYPB-VOTSOKGWSA-N
Application
Pinosylvin, a pre-infectious stilbenoid toxin, is used to study its properties as a fungitoxin and therapeutic agent. Pinosylvin is used as a representative stilbene to study its biological actions and therapeutic value in processes such as cell survival, apoptosis and cell mobility.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Disclaimer
sensitive to oxidation
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signalword
Warning
hcodes
Hazard Classifications
Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
高风险级别生物产品--毒素类产品
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Viera Jančinová et al.
Acta pharmacologica Sinica, 33(10), 1285-1292 (2012-07-31)
To investigate the effects of the naturally occurring stilbenoid pinosylvin on neutrophil activity in vitro and in experimental arthritis, and to examine whether protein kinase C (PKC) activation served as an assumed target of pinosylvin action. Fresh human blood neutrophils
Eun-Jung Park et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 27(3-4), 353-362 (2011-04-08)
Since inhibitors of inducible nitric oxide synthase (iNOS) have been considered as potential anti-inflammatory and cancer chemopreventive agents, we have evaluated the inhibitory effects on the production of nitric oxide (NO) in lipopolysaccharide (LPS)-stimulated murine macrophage RAW 264.7 cells with
Mirka Laavola et al.
Molecules (Basel, Switzerland), 24(1) (2019-01-02)
Interleukin-6 (IL-6) is involved in the pathogenesis of various inflammatory diseases, like rheumatoid arthritis (RA). In the present study, we investigated the role of IL-6 in osteoarthritis (OA) patients and the effects of the stilbenoids monomethyl pinosylvin and pinosylvin on
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 56297-5MG | 04061832583730 |