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Merck
CN

56946

Methyl 3,5-diformyl-1-indolizinecarboxylate

≥90% (HPLC)

Synonym(s):

1-Methoxycarbonyl-3,5-indolizinedicarbaldehyde

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About This Item

Empirical Formula (Hill Notation):
C12H9NO4
CAS Number:
Molecular Weight:
231.20
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352209
MDL number:
Assay:
≥90% (HPLC)
Form:
solid
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InChI

1S/C12H9NO4/c1-17-12(16)10-5-9(7-15)13-8(6-14)3-2-4-11(10)13/h2-7H,1H3

SMILES string

[H]C(=O)c1cccc2c(cc(C([H])=O)n12)C(=O)OC

InChI key

ROYXGFIJSNOFGY-UHFFFAOYSA-N

assay

≥90% (HPLC)

form

solid

Application

Methyl 3,5-diformyl-1-indolizinecarboxylate is used as a precolumn-labeling reagent(HPLC, HPCE) for amino acids. It is similar to but 3x more sensitive than o-phthaldialdehyde (OPA).

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Precolumn-label for amino acids, similar to OPA; but 3 times more sensitive. Described for HPLC and HPCE uses

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Caifu Xue et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(5-6), 317-325 (2011-01-21)
In this paper, microdialysis combining with ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF/MS) was applied to simultaneously identify components in blood and kidney dialysis after oral administration of Abelmoschus manihot extract. Microdialysis probe was implanted in the jugular vein and
Marina Patricia Arrieta et al.
Food chemistry, 135(3), 1511-1519 (2012-09-08)
The simultaneous determination of 17 free amino acids and 8 biogenic amines in Alicante Monastrell wines was investigated for the first time. The quantification was carried out by using a RP-HPLC method, based on a pre-column derivatization with o-phthaldialdehyde (OPA)
S. Oguri et al.
Analyst, 120, 63-63 (1995)

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