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Merck
CN

57857

Lithium iodoacetate

≥97.0% (NT)

Synonym(s):

Iodoacetic acid lithium salt

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About This Item

Linear Formula:
ICH2COOLi
CAS Number:
Molecular Weight:
191.88
UNSPSC Code:
12352103
NACRES:
NA.25
PubChem Substance ID:
EC Number:
265-905-7
Beilstein/REAXYS Number:
4208524
MDL number:
Assay:
≥97.0% (NT)
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InChI key

RZCFQIDTJPHHFJ-UHFFFAOYSA-M

InChI

1S/C2H3IO2.Li/c3-1-2(4)5;/h1H2,(H,4,5);/q;+1/p-1

SMILES string

[Li+].[O-]C(=O)CI

assay

≥97.0% (NT)

impurities

≤3% water

mp

239 °C (dec.) (lit.), ~245 °C (dec.)

Quality Level

Related Categories

Application

Lithium iodoacetate, a halogenacetate, is a lithium salt of iodoacetate that may be used in the study of cysteine peptidases.

Other Notes

Sales restrictions may apply

Disclaimer

May discolor to yellow on storage

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Yun Ju Woo et al.
Experimental & molecular medicine, 43(10), 561-570 (2011-07-29)
Osteoarthritis (OA) is an age-related joint disease that is characterized by degeneration of articular cartilage and chronic pain. Oxidative stress is considered one of the pathophysiological factors in the progression of OA. We investigated the effects of grape seed proanthocyanidin
Ehrenberg et al.
Acta crystallographica. Section B, Structural science, 55(Pt 4), 517-524 (2000-08-06)
Most halogenoacetates of alkali salts readily undergo a thermally induced polymerization reaction to poly-(hydroxyacetic acid) in the solid state. The lithium salts represent a remarkable exception. The crystal structures of lithium chloroacetate, lithium bromoacetate and lithium iodoacetate were determined ab
Runqiang Yang et al.
Journal of the science of food and agriculture, 91(13), 2437-2442 (2011-06-28)
Proteases have become an essential part of the modern food and feed industry, being incorporated in a large and diversified range of products for human and animal consumption. The objective of this study was to purify and characterise a protease
Sébastien Goutal et al.
Drug delivery and translational research, 8(3), 536-542 (2018-01-03)
Elacridar (GF120918) is a highly potent inhibitor of both P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2), the main efflux transporters expressed at the blood-brain barrier (BBB). Elacridar shows very low aqueous solubility, which complicates its formulation for i.v. administration.
Sébastien Goutal et al.
Journal of pharmaceutical and biomedical analysis, 123, 173-178 (2016-02-26)
In clinical practice, rifampicin exposure is estimated from its concentration in venous blood samples. In this study, we hypothesized that differences in rifampicin concentration may exist between arterial and venous plasma. An HPLC-UV method for determining rifampicin concentration in plasma

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