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Merck
CN

62639

Lowicryl® K4M reagent kit

Synonym(s):

HMDSO

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About This Item

CAS Number:
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
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SMILES string

OC(=O)c1ccc2ccc3cccc4ccc1c2c34

impurities

methacrylates (not stabilized)

suitability

suitable for microscopy

application(s)

hematology
histology

storage temp.

2-8°C

Application

Polar, methacrylate/acrylate based, low- temperature embedding resin for biological material. Can be used with either the progressive lowering of temperature technique or freeze substitution.; Applicable temperature range, 220K to 340K

Legal Information

Lowicryl is a registered trademark of Polysciences

pictograms

Skull and crossbonesCorrosion

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Skin Corr. 1B

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

194.0 °F - closed cup

flash_point_c

90 °C - closed cup

Regulatory Information

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D R Abrahamson
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 34(7), 847-853 (1986-07-01)
Ultrastructural distribution of laminin within renal glomerular (GBM) and tubular basement membranes (TBM) was investigated using post-embedding immunolocalization with colloidal gold. Rat kidneys were fixed with 4% formaldehyde and embedded at 4 degrees C in Lowicryl K4M medium. Thin sections
A Booke et al.
Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B, 41(1), 35-41 (1994-03-01)
Eight monoclonal antibodies (MAbs) were tested for the use in immunogold staining of Sindbis virus (SIN) antigen in cultured Baby Hamster kidney (BHK) cells. The antibodies were directed against the capsid (C) protein (5) or against the glycoprotein E1 (3)
K Torihara et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 43(3), 299-305 (1995-03-01)
We demonstrated anionic sites on the lateral wall of cochlear duct and Reissner's membrane (RM) of ICR mice by Lowicryl K4M resin post-embedding and poly-L-lysine-colloidal gold conjugate (PL-CG) as a polycationic probe. The basement membrane and endolymphatic cell surface of
M E Rubio et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 42(3), 405-416 (1994-03-01)
The glycoconjugates in the cytoplasm of inner ear interdental cells and those constituting the limbal tectorial membrane were identified by a post-embedding cytochemical method using low-temperature embedding in Lowicryl K4M and labeling with biotinylated lectins, goat anti-biotin antibody, rabbit anti-goat
B G Schneider et al.
Investigative ophthalmology & visual science, 27(5), 679-688 (1986-05-01)
Interstitial retinol binding protein (IRBP) is a soluble glycoprotein found in the interphotoreceptor matrix (IPM) and implicated in shuttling retinol between retina and pigment epithelium (PE) cells. The authors have studied the distribution of IRBP by EM immunocytochemistry. Thin sections

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