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63226

Benzamidine hydrochloride 1 M solution

Name: Benzamidine hydrochloride 1 M solution
Brand: SIGMA

Synonym(s):

Benzamidine hydrochloride solution, Additive Screening Solution 37/Kit-No 78374

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About This Item

CAS Number:

1670-14-0

NACRES:

NA.26

PubChem Substance ID:

57651918

UNSPSC Code:

12352202

MDL number:

MFCD00013025

Quality level:

100

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storage temp.

2-8°C

Quality Level

100

SMILES string

Cl.NC(=N)c1ccccc1

InChI

1S/C7H8N2.ClH/c8-7(9)6-4-2-1-3-5-6;/h1-5H,(H3,8,9);1H

InChI key

LZCZIHQBSCVGRD-UHFFFAOYSA-N

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves

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Trypsin-ligand binding free energies from explicit and implicit solvent simulations with polarizable potential.

Dian Jiao et al.

Journal of computational chemistry, 30(11), 1701-1711 (2009-04-29)

We have calculated the binding free energies of a series of benzamidine-like inhibitors to trypsin with a polarizable force field using both explicit and implicit solvent approaches. Free energy perturbation has been performed for the ligands in bulk water and

Limitations of conventional inhibitor classifications.

Ryan Walsh et al.

Integrative biology : quantitative biosciences from nano to macro, 3(12), 1197-1201 (2011-11-01)

Enzyme inhibitors are usually classified as competitive, non-competitive or mixed non-competitive. Each of these designations has a serious limitation in that it only describes an extreme of inhibitory behaviour. The non-competitive inhibition equation only considers an approach to complete inhibition

1,2-ethane bis-1-amino-4-benzamidine is active against several brain insult and seizure challenges through anti-NMDA mechanisms targeting the 3H-TCP binding site and antioxidant action.

Joseph Vamecq et al.

European journal of medicinal chemistry, 45(7), 3101-3110 (2010-04-30)

Five bis-benzamidines were screened towards murine magnesium deficiency-dependent audiogenic seizures, unravelling two compounds with efficacious doses 50 (ED(50)) less than 10mg/kg. They were also screened against maximal electroshock and subcutaneous pentylenetetrazole-induced seizures, and explored for superoxide -scavenging activity. 1,2-Ethane bis-1-amino-4-benzamidine

Single-molecule approach to DNA minor-groove association dynamics.

Jorge Bordello et al.

Angewandte Chemie (International ed. in English), 51(30), 7541-7544 (2012-06-16)

Interaction of proteinase inhibitors with Cry1Ac toxicity and the presence of 15 chymotrypsin cDNAs in the midgut of the tobacco budworm, Heliothis virescens (F.) (Lepidoptera: Noctuidae).

Yu Cheng Zhu et al.

Pest management science, 68(5), 692-701 (2012-01-10)

The potential development of resistance to Bacillus thuringiensis (Bt) cotton and surging of non-targeted insects is a major risk in the durability of Bt plant technology. Midgut proteinases are involved in Bt activation and degradation. Proteinase inhibitors may be used

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Global Trade Item Number

SKU	GTIN
8530950025	04027269099893
483818-1G	04061826672327
483818-5G	04061833330661
63226-1ML-F	04061838063182

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