68373
Visfatin human, recombinant from E. coli
≥90% (GE)
Synonym(s):
PBEF, Pre-B cell colony-enhancing factor
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About This Item
NACRES:
NA.77
UNSPSC Code:
12352200
Product Name
Visfatin human, recombinant from E. coli, ≥90% (GE)
assay
≥90% (GE)
form
solid
technique(s)
western blot: suitable
impurities
≤0.1 EU/μg protein endotoxin
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... NAMPT(10135)
Application
Western blotting
Analysis Note
Endotoxin: <0.1 EU/μg protein (LAL test)
General description
Visfatin, also known as pre-B cell colony-enhancing factor, is a cytokine that is highly expressed in visceral fat and was originally isolated as a secreted factor that synergizes with IL-7 and stem cell factors to promote the growth of B cell precursors
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Miao-Pei Chen et al.
The Journal of clinical endocrinology and metabolism, 91(1), 295-299 (2005-10-20)
Visfatin (also known as pre-B cell colony-enhancing factor or PBEF) is a cytokine that is highly expressed in visceral fat and whose blood levels correlate with obesity. Originally isolated as a secreted factor that promotes the growth of B cell
Janin Berndt et al.
Diabetes, 54(10), 2911-2916 (2005-09-28)
Visceral and subcutaneous adipose tissue display important metabolic differences that underlie the association of visceral obesity with obesity-related cardiovascular and metabolic alterations. Recently, visfatin was identified as an adipokine, which is predominantly secreted from visceral adipose tissue both in humans
Mélodie Diot et al.
Reproduction (Cambridge, England), 150(1), 53-63 (2015-04-29)
In mammals, nicotinamide phosphoribosyltransferase (NAMPT) is an adipokine produced by adipose tissue that is found in intracellular and extracellular compartments. The intracellular form of NAMPT is a nicotinamide phosphoribosyltransferase, whereas the extracellular form is considered an adipokine. In humans, NAMPT
Gong Cheng et al.
Oncology reports, 34(2), 987-994 (2015-06-13)
Visfatin is considered to be a biomarker in various types of cancers. However, no evidence has been reported for the direct effect of visfatin on osteosarcoma cell metastasis. The aims of the present study were to investigate the influence of
Xiaoqun Lv et al.
Journal of Cancer, 6(9), 849-858 (2015-08-19)
Colorectal cancer (CRC) is the third most common cancer disease. Here we examined Nampt expression in patients with CRC and the effect of Nampt on cell viability in CRC cells. Nampt protein was overexpressed in colorectal adenoma as well as
Articles
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脂肪组织中的胰岛素耐受性减少了循环游离脂肪酸的摄入，并增加了脂肪酶对储存甘油三酯的水解。了解与胰岛素耐受性相关的激素、细胞因子和脂肪因子。
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