68891
1,4-Butanediol 4 M solution
Synonym(s):
1,4-Butanediol solution, Additive Screening Solution 04/Kit-No 78374
InChI
1S/C4H10O2/c5-3-1-2-4-6/h5-6H,1-4H2
SMILES string
OCCCCO
InChI key
WERYXYBDKMZEQL-UHFFFAOYSA-N
storage temp.
2-8°C
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Xin Zhang et al.
Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 27(12), 1749-1754 (2012-04-18)
Besides medical application, 4-hydroxybutyrate (4-HB) is a precursor of P3HB4HB, a bioplastic showing excellent physical properties and degradability. Escherichia coli S17-1 (pZL-dhaT-aldD) can transform 1, 4-butanediol (1,4-BD) into 4HB with participation of cofactor NAD. To enhance productivity, nicotinic acid phosphoribosyltransferase
Qin Zhou et al.
Metabolic engineering, 13(6), 777-785 (2011-10-26)
Conversion of 3-hydroxypropionate (3HP) from 1,3-propanediol (PDO) was improved by expressing dehydratase gene (dhaT) and aldehyde dehydrogenase gene (aldD) of Pseudomonas putida KT2442 under the promoter of phaCAB operon from Ralstonia eutropha H16. Expression of these genes in Aeromonas hydrophila
Anders Hamberg et al.
Chemical communications (Cambridge, England), 48(80), 10013-10015 (2012-09-05)
The enzyme Candida antarctica lipase B was subjected to site directed mutagenesis suggested by molecular modelling. The selectivity for the enzyme increased towards a range of diols over their corresponding monoesters as an effect of the mutations.
New recreational drugs and the primary care approach to patients who use them.
Adam R Winstock et al.
BMJ (Clinical research ed.), 344, e288-e288 (2012-02-18)
Amy K Goodwin et al.
Psychopharmacology, 225(3), 637-646 (2012-09-05)
Gamma-butyrolactone (GBL) and 1,4-butanediol (1,4-BD) are gamma-hydroxybutyrate (GHB) pro-drugs and drugs of abuse. Given the reports of abuse, and the ease at which GBL and 1,4-BD may be obtained, we investigated the reinforcing effects of GBL (n = 5) and 1,4-BD (n = 4)
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