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Merck
CN

68998

Esterase Isoenzyme 4 porcine liver, recombinant

recombinant, expressed in E. coli, ≥0.7 U/mg

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About This Item

CAS Number:
UNSPSC Code:
12352204
EC Number:
232-773-7
NACRES:
NA.54
Specific activity:
≥0.7 U/mg
Recombinant:
expressed in E. coli
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recombinant

expressed in E. coli

form

crystalline, crystals, powder or flakes

specific activity

≥0.7 U/mg

storage temp.

−20°C

Quality Level

Application

Esterase Isoenzymes may be used to identify the monocytic element in normal and leukemic cells. They may be used for the biochemical characterization of different hematopoietic cell lineages and stages of differentiation when studying leukemias and lymphomas. Esterase Isoenzyme 4, product 68998, is recombinant and from porcine liver. It is expressed in E. coli.

Biochem/physiol Actions

An esterase is a hydrolase that splits esters into acids and alcohols.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

1 U corresponds to the amount of enzyme which converts 1 μmol 4-nitrophenyl-L-acetate per minute at pH 7.5 and 30°C.

pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Esterase isoenzyme profiles of 255 leukemia-lymphoma cell lines from all hematopoietic cell lineages.
SM Gignac, ZB Hu, et al.
Leukemia Lymphoma, 22, 143-151 (1996)
H G Drexler et al.
Cancer, 59(1), 77-82 (1987-01-01)
The expression of a particular alpha-naphthyl acetate esterase isoenzyme which is specific for monocytes was examined in a panel of cultured leukemia-lymphoma cell lines (n = 88), freshly obtained leukemia-lymphoma cells (n = 527), and in fresh (n = 10)
Ian Cushman et al.
The Journal of biological chemistry, 288(26), 19177-19183 (2013-05-10)
A number of proteins that play key roles in cell signaling are post-translationally modified by the prenylation pathway. The final step in this pathway is methylation of the carboxyl terminus of the prenylated protein by isoprenylcysteine carboxylmethyltransferase. Due to the
Noboru Yamamoto et al.
Cancer chemotherapy and pharmacology, 71(6), 1645-1655 (2013-04-26)
LY2334737 is an oral gemcitabine prodrug. This Phase I study assessed the safety and tolerability of LY2334737 in Japanese patients with solid tumors and evaluated pharmacokinetics (PK), pharmacodynamics, and antitumor activity. Patients with advanced/metastatic solid tumors received escalating doses of
Takashi Nishiyama et al.
Acta crystallographica. Section D, Biological crystallography, 69(Pt 1), 44-51 (2013-01-01)
Bacterial biofilm formation is an extremely widespread phenomenon involving the secretion of a protective exopolysaccharide matrix which helps the bacteria to attach to surfaces and to overcome a variety of stresses in different environments. This matrix may also include proteins

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