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Merck
CN

69769

Microperoxidase disodium salt from horse heart

≥85% (HPCE)

Synonym(s):

H-11-PT, Haeme undecapeptide, MP-11

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About This Item

Empirical Formula (Hill Notation):
C84H114FeN20Na2O21S2
CAS Number:
Molecular Weight:
1905.88
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352108
MDL number:
Assay:
≥85% (HPCE)
Form:
powder
Solubility:
H2O: 10 mg/mL, clear, dark red-brown
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assay

≥85% (HPCE)

form

powder

impurities

peroxidase activity, ≤10% water

solubility

H2O: 10 mg/mL, clear, dark red-brown

storage temp.

−20°C

SMILES string

O.O.O.O.[Na+].[Na+].CC(C)[C@H](N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@H]1CSSC(C)c2c(C)c3nc2nc4c(C)c(CCC([O-])=O)c5nc6nc(nc7c(C)c(C(C)SSC[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC1=O)C(=O)N[C@@H](Cc8c[nH]cn8)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(O)=O)C(O)=O)c(n3)n7[Fe]n45)c(C)c6CCC([O-])=O

InChI

1S/C80H113N23O22S4.Fe.2Na.4H2O/c1-32(2)59(83)77(121)89-47(19-24-55(110)111)72(116)88-45(15-13-14-26-81)71(115)92-50-29-126-128-41(12)58-37(8)65-101-68(58)99-63-35(6)44(17-23-54(108)109)67(98-63)103-66-43(16-22-53(106)107)34(5)62(97-66)96-64-36(7)57(69(100-64)102-65)40(11)129-127-30-51(93-73(117)46(18-21-52(82)105)87-70(114)38(9)86-75(50)119)76(120)91-49(27-42-28-84-31-85-42)74(118)95-61(39(10)104)79(123)94-60(33(3)4)78(122)90-48(80(124)125)20-25-56(112)113;;;;;;;/h28,31-33,38-41,45-51,59-61,104H,13-27,29-30,81,83H2,1-12H3,(H20,82,84,85,86,87,88,89,90,91,92,93,94,95,96,97,98,99,100,101,102,103,105,106,107,108,109,110,111,112,113,114,115,116,117,118,119,120,121,122,123,124,125);;;;4*1H2/q;+2;2*+1;;;;/p-4/t38-,39+,40?,41?,45-,46-,47-,48-,49-,50-,51-,59-,60-,61-;;;;;;;/m0......./s1

InChI key

HARTZTRJJQAYAK-FJHAOVHCSA-J

General description

Val-Glu-Lys-(Cys-Ala-Gln-Cys)Heme-His-Thr-Val-Glu

Preparation Note

prepared by enzymatic degradation of horse heart cytochrome c

Other Notes

Cationic heme undecapeptide as stain for detecting glycosaminoglycans on cellulose acetate; Kinetic study of pH-dependent properties
Sales restrictions may apply


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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M T Wilson et al.
European journal of biochemistry, 77(1), 193-199 (1977-07-01)
The ferric form of the haem undecapeptide, derived from horse cytochrome c by peptic digestion, undergoes at least three pH-induced transitions with pK values of 3.4, 5.8 and 7.6. Temperature-jump experiments suggest that the first of these is due to
N Ghinea
Analytical biochemistry, 155(1), 78-82 (1986-05-15)
A rapid and sensitive method has been developed for detecting glycosaminoglycans on cellulose acetate strips. The method is based on the electrostatic interactions between glycosaminoglycans and cationic heme undecapeptide. The complexes are identified by peroxidatic reaction using 3,3'-diaminobenzidine as H2



Global Trade Item Number

SKUGTIN
69769-250MG04061832532981
69769-50MG04061832532998
69769-10MG04061832532974