77857
Ketoreductase
recombinant, expressed in E. coli, ≥0.2 U/mg
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About This Item
CAS Number:
UNSPSC Code:
12352204
EC Number:
232-823-8
MDL number:
Specific activity:
≥0.2 U/mg
Recombinant:
expressed in E. coli
recombinant
expressed in E. coli
form
powder
specific activity
≥0.2 U/mg
storage temp.
2-8°C
Application
Ketoreductases are used to study the stereospecificity of ketoreductase domains . They may be used to reduce precursors of α-chloroalcohols, which are synthetic intermediates for various pharmaceutical compounds .
Biochem/physiol Actions
Ketoreductase, Product 77857, reduces 4-chloroacetoacetate with NADPH as a cosubstrate.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Other Notes
1 U corresponds to the amount of enzyme which reduces 1 μmol 4-chloroacetoacetate per minute at pH 6.0 and 25°C (cosubstrate NADPH).
signalword
Danger
hcodes
Hazard Classifications
Resp. Sens. 1 - Skin Sens. 1
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Roselyne Castonguay et al.
Journal of the American Chemical Society, 130(35), 11598-11599 (2008-08-13)
Tylactone synthase (TYLS) is a modular polyketide synthase that catalyzes the formation of tylactone (1), the parent aglycone precursor of the macrolide antibiotic tylosin. TYLS modules 1 and 2 are responsible for the generation of antidiketide and triketide intermediates, respectively
Automation Highlights from the Literature
Kerstin Thurow and Hilmar Weinmann
Journal of Laboratory Automation, 11, 1-6 (2006)
João R M Almeida et al.
Applied microbiology and biotechnology, 78(6), 939-945 (2008-03-12)
Saccharomyces cerevisiae alcohol dehydrogenases responsible for NADH-, and NADPH-specific reduction of the furaldehydes 5-hydroxymethyl-furfural (HMF) and furfural have previously been identified. In the present study, strains overexpressing the corresponding genes (mut-ADH1 and ADH6), together with a control strain, were compared
Global Trade Item Number
| SKU | GTIN |
|---|---|
| P5172-1MG | 04061834376750 |
| P5172-5MG | 04061832785868 |
| 538909-1MG | 04055977195248 |
| P5172-10MG | 04061832785851 |