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Merck
CN

78438

Dy-615 NHS ester

suitable for fluorescence

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About This Item

Empirical Formula (Hill Notation):
C36H41N3O8S
Molecular Weight:
675.79
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
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InChI

1S/C36H41N3O8S/c1-35(2,3)31-20-23(26-15-13-24(37)21-29(26)46-31)10-9-11-30-36(4,5)27-22-25(48(43,44)45)14-16-28(27)38(30)19-8-6-7-12-34(42)47-39-32(40)17-18-33(39)41/h9-11,13-16,20-22H,6-8,12,17-19,37H2,1-5H3/b10-9+,30-11+

SMILES string

CC(C)(C)c1cc(\C=C\C=C2\N(CCCCCC(=O)ON3C(=O)CCC3=O)c4ccc(cc4C2(C)C)S([O-])(=O)=O)c5ccc(N)cc5[o+]1

InChI key

NIOGLMJYJBEELX-GINSVCLMSA-N

form

powder

fluorescence

λex 610 nm; λem 631 nm in 0.1 M phosphate pH 7.0

suitability

corresponds for coupling to amines, suitable for fluorescence

storage temp.

2-8°C

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Yuliya Voskobiynyk et al.
PLoS genetics, 17(1), e1009195-e1009195 (2021-01-08)
Dravet syndrome (DS) is a developmental and epileptic encephalopathy that results from mutations in the Nav1.1 sodium channel encoded by SCN1A. Most known DS-causing mutations are in coding regions of SCN1A, but we recently identified several disease-associated SCN1A mutations in

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