79470
D(+)-2-Phosphoglyceric acid sodium salt hydrate
≥75% (calc. on dry substance, enzymatic)
Synonym(s):
D-Glycerate 2-phosphate sodium salt, Sodium D-2-phosphoglycerate hydrate
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About This Item
Empirical Formula (Hill Notation):
C3H7O7P · xNa+ · yH2O
CAS Number:
Molecular Weight:
186.06 (anhydrous free acid basis)
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.26
Assay:
≥75% (calc. on dry substance, enzymatic)
Form:
powder
Quality Segment
assay
≥75% (calc. on dry substance, enzymatic)
form
powder
impurities
≤1% Pi, ≤35% water
storage temp.
−20°C
SMILES string
O=C(O)[C@@H](CO)OP(O)(O)=O.C.C
InChI key
PXJAQZYAJDMQJH-YBBRRFGFSA-N
Biochem/physiol Actions
Enantiomerically pure metabolite of glycolysis/gluconeogenesis and also substrate for a number of important enzymes in central metabolism like enolase and phosphoglycerate mutase.
The enzyme enolase is responsible for reversible conversion of 2-phosphoglycerate (2-PG) into phosphoenolpyruvate (PEP). Phosphoglycerate mutase causes reversible isomerization of 3-phosphoglycerate and 2-phosphoglycerate in glycolysis and gluconeogenesis.
Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
Eyeshields, Gloves, type N95 (US)
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Articles
Warburg effect enhances glucose to lactate conversion in tumor cells, regardless of oxygen levels; impacting cancer metabolism since 1924.
本页面介绍了一篇有关瓦博格效应的文章，以及其如何能够在正常氧气水平下，增强肿瘤细胞中葡萄糖向乳酸的转化。Otto Heinrich Warburg在1924年证明，癌细胞显示出对糖酵解的依赖性增加，以满足他们的能量需求，无论是否有充足的氧气存在。
Molecular characterization of phosphoglycerate mutase in archaea.
van der Oost J, et al.
FEMS Microbiology Letters, 212, 111-120 (2002)
Cloning, expression and characterization of an extracellular enolase from Leuconostoc mesenteroides.
Jin-Ha Lee et al.
FEMS microbiology letters, 259(2), 240-248 (2006-06-01)
Enolase on the surface of streptococci putatively facilitates pathogenic invasion of the host organisms. The related Leuconostoc mesenteroides 512FMCM is nonpathogenic, but it too has an extracellular enolase. Purified isolates of extracellular dextransucrase from cultures of L. mesenteroides contain minute
T M Larsen et al.
Biochemistry, 35(14), 4349-4358 (1996-04-09)
The equilibrium mixture of yeast enolase with substrate, 2-phospho-D-glycerate (2-PGA), and product, phosphoenolpyruvate (P-enolpyruvate), has been crystallized from solutions of poly(ethylene glycol) (PEG) at pH 8.0. Crystals belong to the space group C2 and have unit cell dimensions a =
Global Trade Item Number
| SKU | GTIN |
|---|---|
| Y0001237 | 04061833797372 |
| N1016-5G | 04061835516155 |
| N1016-25G | 04061832785691 |
| N0845000 | 04061834093114 |
| PHR1336-1G | 04061835233687 |
| N1016-1G | 04061835557851 |
| N0845000-100MG | 04061833824887 |
| 79470-250MG | 04061833046524 |
| 79470-50MG | 04061833046531 |
| 79470-1G | 04061826681107 |