80198
Methoxatin disodium salt
≥97.0% (HPLC)
Synonym(s):
PQQ, Pyrrolo-quinoline-quinone disodium salt
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About This Item
Empirical Formula (Hill Notation):
C14H4N2Na2O8
CAS Number:
Molecular Weight:
374.17
NACRES:
NA.79
PubChem Substance ID:
UNSPSC Code:
12352005
MDL number:
biological source
fermentation/recombinant
Quality Segment
assay
≥97.0% (HPLC)
form
powder
color
red-brown to deep orange, red-brown to deep red-brown
storage temp.
2-8°C
SMILES string
OC(=O)c1cc(nc2C(=O)C(=O)c3cc([nH]c3-c12)C(=O)O[Na])C(=O)O[Na]
InChI
1S/C14H6N2O8.2Na/c17-10-4-2-6(14(23)24)15-8(4)7-3(12(19)20)1-5(13(21)22)16-9(7)11(10)18;;/h1-2,15H,(H,19,20)(H,21,22)(H,23,24);;/q;2*+1/p-2
InChI key
UFVBOGYDCJNLPM-UHFFFAOYSA-L
General description
Methoxatin/pyrroloquinoline quinone (PQQ) is mostly seen in plants, few bacteria and single cell eukaryotes, like yeast. It is mainly obtained from methylotrophic bacteria. PQQ may also present in the tissues of mammals.
Application
- Safety assessment of a novel, dietary pyrroloquinoline quinone disodium salt (mnemoPQQ): This study investigates the safety profile of Methoxatin disodium salt, which has implications for its application in assay development for clinical and diagnostic purposes. Specifically, it addresses the compound′s use in dietary supplements and potential crossover into clinical assays where safety and toxicity are paramount (Shiojima et al., 2022).
Biochem/physiol Actions
In bacteria, pyrroloquinoline quinone (PQQ) is used as a redox cycling cofactor. It acts as a cofactor (prosthetic group) for enzyme-catalyzed redox reactions of glucose and methanol dehydrogenase(s). PQQ is used in liposomes to establish a simple homogeneous assay for the detection of membrane permeabilization by antimicrobial peptides and synthetic copolymers. In bovine plasma amine oxidase, methoxatin may acts as the cofactor.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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