84071
Ruthenium Red
≥85% (calc. on dry substance, AT)
Synonym(s):
Ammoniated ruthenium oxychloride
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About This Item
Linear Formula:
[(NH3)5RuORu(NH3)4ORu(NH3)5]Cl6
CAS Number:
Molecular Weight:
786.35
PubChem Substance ID:
UNSPSC Code:
12171500
Colour Index Number:
77800
MDL number:
Quality Level
assay
≥85% (calc. on dry substance, AT)
impurities
~5% water
suitability
suitable for microscopy
SMILES string
N.N.N.N.N.N.N.N.N.N.N.N.N.N.[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Ru++]O[Ru++]O[Ru++]
InChI
1S/6ClH.14H3N.2O.3Ru/h6*1H;14*1H3;;;;;/q;;;;;;;;;;;;;;;;;;;;;;3*+2/p-6
InChI key
ZXYSDUPLHOJIOR-UHFFFAOYSA-H
Application
Inhibits mitochondrial Ca2+ uniporter; capsaicin antagonist; blocks VR1 vanilloid receptor-coupled ion channels.
Other Notes
Interaction with calcium-binding proteins
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Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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J H Charuk et al.
Analytical biochemistry, 188(1), 123-131 (1990-07-01)
The interaction of ruthenium red, [(NH3)5Ru-O-Ru(NH3)4-O-Ru(NH3)5]Cl6.4H2O, with various Ca2(+)-binding proteins was studied. Ruthenium red inhibited Ca2+ binding to the sarcoplasmic reticulum protein, calsequestrin, immobilized on Sepharose 4B. Furthermore, ruthenium red bound to calsequestrin with high affinity (Kd = 0.7 microM;
Cyrielle Corbin et al.
Ultrasonics sonochemistry, 26, 176-185 (2015-03-11)
Flaxseed accumulates in its seedcoat a macromolecular complex composed of lignan (secoisolariciresinol diglucoside, SDG), flavonol (herbacetin diglucoside, HDG) and hydroxycinnamic acids (p-couramic, caffeic and ferulic acid glucosides). Their antioxidant and/or cancer chemopreventive properties support their interest in human health and
Gregory M Pask et al.
PloS one, 6(12), e28774-e28774 (2011-12-17)
Insect odorant receptors (ORs) function as odorant-gated ion channels consisting of a conventional, odorant-binding OR and the Orco coreceptor. While Orco can function as a homomeric ion channel, the role(s) of the conventional OR in heteromeric OR complexes has largely