84071
Ruthenium Red
≥85% (calc. on dry substance, AT)
Synonym(s):
Ammoniated ruthenium oxychloride
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About This Item
Linear Formula:
[(NH3)5RuORu(NH3)4ORu(NH3)5]Cl6
CAS Number:
Molecular Weight:
786.35
Colour Index Number:
77800
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
Quality Level
Assay
≥85% (calc. on dry substance, AT)
impurities
~5% water
suitability
suitable for microscopy
SMILES string
N.N.N.N.N.N.N.N.N.N.N.N.N.N.[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Ru++]O[Ru++]O[Ru++]
InChI
1S/6ClH.14H3N.2O.3Ru/h6*1H;14*1H3;;;;;/q;;;;;;;;;;;;;;;;;;;;;;3*+2/p-6
InChI key
ZXYSDUPLHOJIOR-UHFFFAOYSA-H
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Application
Inhibits mitochondrial Ca2+ uniporter; capsaicin antagonist; blocks VR1 vanilloid receptor-coupled ion channels.
Other Notes
Interaction with calcium-binding proteins
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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J H Charuk et al.
Analytical biochemistry, 188(1), 123-131 (1990-07-01)
The interaction of ruthenium red, [(NH3)5Ru-O-Ru(NH3)4-O-Ru(NH3)5]Cl6.4H2O, with various Ca2(+)-binding proteins was studied. Ruthenium red inhibited Ca2+ binding to the sarcoplasmic reticulum protein, calsequestrin, immobilized on Sepharose 4B. Furthermore, ruthenium red bound to calsequestrin with high affinity (Kd = 0.7 microM;
Lijie Xuan et al.
Plant, cell & environment, 41(12), 2773-2790 (2018-07-08)
Flavonoids are involved in many physiological processes in plants. TRANSPARENT TESTA 4 (TT4) acts at the first step of flavonoid biosynthesis, and the loss of TT4 function causes a lack of flavonoid. Flavonoid deficiency is reportedly the main cause of
Gregory M Pask et al.
PloS one, 6(12), e28774-e28774 (2011-12-17)
Insect odorant receptors (ORs) function as odorant-gated ion channels consisting of a conventional, odorant-binding OR and the Orco coreceptor. While Orco can function as a homomeric ion channel, the role(s) of the conventional OR in heteromeric OR complexes has largely
Cyrielle Corbin et al.
Ultrasonics sonochemistry, 26, 176-185 (2015-03-11)
Flaxseed accumulates in its seedcoat a macromolecular complex composed of lignan (secoisolariciresinol diglucoside, SDG), flavonol (herbacetin diglucoside, HDG) and hydroxycinnamic acids (p-couramic, caffeic and ferulic acid glucosides). Their antioxidant and/or cancer chemopreventive properties support their interest in human health and
Marco Schlepütz et al.
PloS one, 7(10), e47344-e47344 (2012-10-12)
The peripheral airway innervation of the lower respiratory tract of mammals is not completely functionally characterized. Recently, we have shown in rats that precision-cut lung slices (PCLS) respond to electric field stimulation (EFS) and provide a useful model to study
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