84071
Ruthenium Red
≥85% (calc. on dry substance, AT)
Synonym(s):
Ammoniated ruthenium oxychloride
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About This Item
Linear Formula:
[(NH3)5RuORu(NH3)4ORu(NH3)5]Cl6
CAS Number:
Molecular Weight:
786.35
PubChem Substance ID:
UNSPSC Code:
12171500
Colour Index Number:
77800
MDL number:
InChI
1S/6ClH.14H3N.2O.3Ru/h6*1H;14*1H3;;;;;/q;;;;;;;;;;;;;;;;;;;;;;3*+2/p-6
InChI key
ZXYSDUPLHOJIOR-UHFFFAOYSA-H
assay
≥85% (calc. on dry substance, AT)
impurities
~5% water
suitability
suitable for microscopy
Quality Level
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Application
Inhibits mitochondrial Ca2+ uniporter; capsaicin antagonist; blocks VR1 vanilloid receptor-coupled ion channels.
Other Notes
Interaction with calcium-binding proteins
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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J H Charuk et al.
Analytical biochemistry, 188(1), 123-131 (1990-07-01)
The interaction of ruthenium red, [(NH3)5Ru-O-Ru(NH3)4-O-Ru(NH3)5]Cl6.4H2O, with various Ca2(+)-binding proteins was studied. Ruthenium red inhibited Ca2+ binding to the sarcoplasmic reticulum protein, calsequestrin, immobilized on Sepharose 4B. Furthermore, ruthenium red bound to calsequestrin with high affinity (Kd = 0.7 microM;
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